Population genetics of sexual conflict in the genomic era

JE Mank - Nature Reviews Genetics, 2017 - nature.com
Sexual conflict occurs when selection acts in opposing directions on males and females.
Case studies in both vertebrates and invertebrates indicate that sexual conflict maintains …

Two sexes, one genome: the evolutionary dynamics of intralocus sexual conflict

TM Pennell, EH Morrow - Ecology and evolution, 2013 - Wiley Online Library
As the evolutionary interests of males and females are frequently divergent, a trait value that
is optimal for the fitness of one sex is often not optimal for the other. A shared genome also …

Single-cell RNA-seq of Drosophila miranda testis reveals the evolution and trajectory of germline sex chromosome regulation

KHC Wei, K Chatla, D Bachtrog - PLoS Biology, 2024 - journals.plos.org
Although sex chromosomes have evolved from autosomes, they often have unusual
regulatory regimes that are sex-and cell-type-specific such as dosage compensation (DC) …

Genome-wide sexually antagonistic variants reveal long-standing constraints on sexual dimorphism in fruit flies

F Ruzicka, MS Hill, TM Pennell, I Flis, FC Ingleby… - PLoS …, 2019 - journals.plos.org
The evolution of sexual dimorphism is constrained by a shared genome, leading to 'sexual
antagonism', in which different alleles at given loci are favoured by selection in males and …

Balancing selection in species with separate sexes: insights from Fisher's geometric model

T Connallon, AG Clark - Genetics, 2014 - academic.oup.com
How common is balancing selection, and what fraction of phenotypic variance is attributable
to balanced polymorphisms? Despite decades of research, answers to these questions …

The search for sexually antagonistic genes: Practical insights from studies of local adaptation and statistical genomics

F Ruzicka, L Dutoit, P Czuppon, CY Jordan… - Evolution …, 2020 - academic.oup.com
Sexually antagonistic (SA) genetic variation—in which alleles favored in one sex are
disfavored in the other—is predicted to be common and has been documented in several …

Asymmetric inheritance: the diversity and evolution of non-Mendelian reproductive strategies

L Ross, AJ Mongue, CN Hodson… - Annual Review of …, 2022 - annualreviews.org
The ability to reproduce is the key trait that distinguishes living organisms from inorganic
matter, and the strategies used to achieve successful reproduction are almost as diverse as …

Is the X chromosome a hot spot for sexually antagonistic polymorphisms? Biases in current empirical tests of classical theory

F Ruzicka, T Connallon - Proceedings of the Royal …, 2020 - royalsocietypublishing.org
Females and males carry nearly identical genomes, which can constrain the evolution of
sexual dimorphism and generate conditions that are favourable for maintaining sexually …

Sexual dimorphism and female ecomorphology in Anolis (Squamata: Anolidae): knowledge of female morphology increases the understanding of Anolis …

JD Rodríguez-Rodríguez… - Biological Journal of …, 2024 - academic.oup.com
The study of sexual dimorphism in Anolis lizards brings the opportunity to understand how
this phenomena interacts with adaptive radiation to produce broader diversity. We explored …

Polygenic signals of sex differences in selection in humans from the UK Biobank

F Ruzicka, L Holman, T Connallon - PLoS Biology, 2022 - journals.plos.org
Sex differences in the fitness effects of genetic variants can influence the rate of adaptation
and the maintenance of genetic variation. For example,“sexually antagonistic”(SA) variants …