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Proactive and reactive roles of TGF-β in cancer
Cancer cells adapt to varying stress conditions to survive through plasticity. Stem cells
exhibit a high degree of plasticity, allowing them to generate more stem cells or differentiate …
exhibit a high degree of plasticity, allowing them to generate more stem cells or differentiate …
Endocytosis and organelle targeting of nanomedicines in cancer therapy
X Wang, Y Qiu, M Wang, C Zhang, T Zhang… - International journal …, 2020 - Taylor & Francis
Nanomedicines (NMs) have played an increasing role in cancer therapy as carriers to
efficiently deliver therapeutics into tumor cells. For this application, the uptake of NMs by …
efficiently deliver therapeutics into tumor cells. For this application, the uptake of NMs by …
[HTML][HTML] Selective surface PEGylation of UiO-66 nanoparticles for enhanced stability, cell uptake, and pH-responsive drug delivery
The high storage capacities and excellent biocompatibilities of metal-organic frameworks
(MOFs) have made them emerging candidates as drug-delivery vectors. Incorporation of …
(MOFs) have made them emerging candidates as drug-delivery vectors. Incorporation of …
How cationic lipids transfer nucleic acids into cells and across cellular membranes: recent advances
Z ur Rehman, IS Zuhorn, D Hoekstra - Journal of Controlled Release, 2013 - Elsevier
Cationic lipid-and polymer-based nanodevices are considered appropriate alternatives for
virus-based particles for delivery of nucleic acids, including genes and siRNA, into …
virus-based particles for delivery of nucleic acids, including genes and siRNA, into …
Effects of serum adsorption on cellular uptake profile and consequent impact of titanium dioxide nanoparticles on human lung cell lines
Exposure to fetal bovine serum (FBS) is shown herein to reduce the aggregate size of
titanium dioxide (TiO2) nanoparticles, affecting uptake and consequent effect on A549 and …
titanium dioxide (TiO2) nanoparticles, affecting uptake and consequent effect on A549 and …
[HTML][HTML] The pore-forming action of polyenes: From model membranes to living organisms
L Kristanc, B Božič, ŠZ Jokhadar, MS Dolenc… - … et Biophysica Acta (BBA …, 2019 - Elsevier
The incidence of resistant fungal pathogens has been increasing, especially in immuno-
compromised people. As such, considerable research has been focused on discovering anti …
compromised people. As such, considerable research has been focused on discovering anti …
Pathways of cellular internalisation of liposomes delivered siRNA and effects on siRNA engagement with target mRNA and silencing in cancer cells
A Alshehri, A Grabowska, S Stolnik - Scientific reports, 2018 - nature.com
Abstract Design of an efficient delivery system is a generally recognised bottleneck in
translation of siRNA technology into clinic. Despite research efforts, cellular processes that …
translation of siRNA technology into clinic. Despite research efforts, cellular processes that …
Ion exchange: an advanced synthetic method for complex nanoparticles
There have been tremendous efforts to develop new synthetic methods for creating novel
nanoparticles (NPs) with enhanced and desired properties. Among the many synthetic …
nanoparticles (NPs) with enhanced and desired properties. Among the many synthetic …
Enterococcus faecalis alters endo-lysosomal trafficking to replicate and persist within mammalian cells
RAG da Silva, WH Tay, FK Ho, FR Tanoto… - PLoS …, 2022 - journals.plos.org
Enterococcus faecalis is a frequent opportunistic pathogen of wounds, whose infections are
associated with biofilm formation, persistence, and recalcitrance toward treatment. We have …
associated with biofilm formation, persistence, and recalcitrance toward treatment. We have …
Cell penetrating peptide-modified poly (lactic-co-glycolic acid) nanoparticles with enhanced cell internalization
The surface modification of nanoparticles (NPs) can enhance the intracellular delivery of
drugs, proteins, and genetic agents. Here we studied the effect of different surface ligands …
drugs, proteins, and genetic agents. Here we studied the effect of different surface ligands …