The relationship between different dimensions of alcohol use and the burden of disease—an update
Background and aims Alcohol use is a major contributor to injuries, mortality and the burden
of disease. This review updates knowledge on risk relations between dimensions of alcohol …
of disease. This review updates knowledge on risk relations between dimensions of alcohol …
Drug–drug interactions between anti-retroviral therapies and drugs of abuse in HIV systems
Introduction: Substance abuse is a common problem among HIV-infected individuals.
Importantly, addictions as well as moderate use of alcohol, smoking, or other illicit drugs …
Importantly, addictions as well as moderate use of alcohol, smoking, or other illicit drugs …
A comprehensive review of cytochrome P450 2E1 for xenobiotic metabolism
Abstract Cytochrome P450 2E1 (CYP2E1) plays a vital role in drug-induced hepatotoxicity
and cancers (eg lung and bladder cancer), since it is responsible for metabolizing a number …
and cancers (eg lung and bladder cancer), since it is responsible for metabolizing a number …
Hepatotoxicity of herbal supplements mediated by modulation of cytochrome P450
CT Brewer, T Chen - International Journal of Molecular Sciences, 2017 - mdpi.com
Herbal supplements are a significant source of drug-drug interactions (DDIs), herb-drug
interactions, and hepatotoxicity. Cytochrome P450 (CYP450) enzymes metabolize a large …
interactions, and hepatotoxicity. Cytochrome P450 (CYP450) enzymes metabolize a large …
Associations between patterns of alcohol use and viral load suppression amongst women living with HIV in South Africa
This study aimed to identify alcohol use patterns associated with viral non-suppression
among women living with HIV (WLWH) and the extent to which adherence mediated these …
among women living with HIV (WLWH) and the extent to which adherence mediated these …
Comparison of self-reported alcohol consumption to phosphatidylethanol measurement among HIV-infected patients initiating antiretroviral treatment in southwestern …
Background Alcohol consumption among HIV-infected patients may accelerate HIV disease
progression or reduce antiretroviral therapy adherence. Self-reported alcohol use is …
progression or reduce antiretroviral therapy adherence. Self-reported alcohol use is …
Does alcohol use have a causal effect on HIV incidence and disease progression? A review of the literature and a modeling strategy for quantifying the effect
In the first part of this review, the nature of the associations between alcohol use and
HIV/AIDS is discussed. Alcohol use has been found to be strongly associated with incidence …
HIV/AIDS is discussed. Alcohol use has been found to be strongly associated with incidence …
Diallyl sulfide: potential use in novel therapeutic interventions in alcohol, drugs, and disease mediated cellular toxicity by targeting cytochrome P450 2E1
Diallyl sulfide (DAS) and other organosulfur compounds are chief constituents of garlic.
These compounds have many health benefits, as they are very efficient in detoxifying natural …
These compounds have many health benefits, as they are very efficient in detoxifying natural …
Cytokine profiling of exosomes derived from the plasma of HIV-infected alcohol drinkers and cigarette smokers
Cytokines and chemokines circulate in plasma and may be transferred to distant sites, via
exosomes. HIV infection is associated with dysregulation of cytokines and chemokines …
exosomes. HIV infection is associated with dysregulation of cytokines and chemokines …
Specific packaging and circulation of cytochromes P450, especially 2E1 isozyme, in human plasma exosomes and their implications in cellular communications
Cytochrome P450 (CYP) enzymes metabolize the majority of xenobiotics and are mainly
found in hepatic and some extra-hepatic cells. However, their presence and functional role …
found in hepatic and some extra-hepatic cells. However, their presence and functional role …