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Novel noninvasive approaches to the treatment of obesity: from pharmacotherapy to gene therapy
Recent insights into the pathophysiologic underlying mechanisms of obesity have led to the
discovery of several promising drug targets and novel therapeutic strategies to address the …
discovery of several promising drug targets and novel therapeutic strategies to address the …
International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB1 and CB2
RG Pertwee, AC Howlett, ME Abood… - Pharmacological …, 2010 - Elsevier
There are at least two types of cannabinoid receptors (CB 1 and CB 2). Ligands activating
these G protein-coupled receptors (GPCRs) include the phytocannabinoid Δ 9 …
these G protein-coupled receptors (GPCRs) include the phytocannabinoid Δ 9 …
Cannabinoid type 2 receptors mediate a cell type-specific plasticity in the hippocampus
Endocannabinoids (eCBs) exert major control over neuronal activity by activating
cannabinoid receptors (CBRs). The functionality of the eCB system is primarily ascribed to …
cannabinoid receptors (CBRs). The functionality of the eCB system is primarily ascribed to …
[HTML][HTML] The effects of cannabidiol, a non-intoxicating compound of cannabis, on the cardiovascular system in health and disease
A Kicman, M Toczek - International journal of molecular sciences, 2020 - mdpi.com
Cannabidiol (CBD) is a non-intoxicating and generally well-tolerated constituent of cannabis
which exhibits potential beneficial properties in a wide range of diseases, including …
which exhibits potential beneficial properties in a wide range of diseases, including …
The essential medicinal chemistry of cannabidiol (CBD)
This Perspective of the published essential medicinal chemistry of cannabidiol (CBD)
provides evidence that the popularization of CBD-fortified or CBD-labeled health products …
provides evidence that the popularization of CBD-fortified or CBD-labeled health products …
Cannabinoid and cannabinoid‐like receptors in microglia, astrocytes, and astrocytomas
N Stella - Glia, 2010 - Wiley Online Library
CB1 and CB2 receptors are activated by a plethora of cannabinoid compounds, be they
endogenously‐produced, plant‐derived or synthetic. These receptors are expressed by …
endogenously‐produced, plant‐derived or synthetic. These receptors are expressed by …
The endocannabinoid system and pain
J Guindon, AG Hohmann - CNS & Neurological Disorders-Drug …, 2009 - ingentaconnect.com
The therapeutic potential of cannabinoids has been the topic of extensive investigation
following the discovery of cannabinoid receptors and their endogenous ligands …
following the discovery of cannabinoid receptors and their endogenous ligands …
An overview on medicinal chemistry of synthetic and natural derivatives of cannabidiol
Cannabidiol (CBD) has been traditionally used in Cannabis-based preparation, however
historically, it has received far less interest as a single drug than the other components of …
historically, it has received far less interest as a single drug than the other components of …
An overview on synthetic and biological activities of cannabidiol (CBD) and its derivatives
X Wang, H Zhang, Y Liu, Y Xu, B Yang, H Li… - Bioorganic Chemistry, 2023 - Elsevier
Cannabidiol is a class of non-psychoactive plant cannabinoids derived from cannabis
plants. Currently, Epidiolex (Cannabidiol) has been approved by the FDA for the treatment of …
plants. Currently, Epidiolex (Cannabidiol) has been approved by the FDA for the treatment of …
Beyond THC and endocannabinoids
Research in the cannabinoid field, namely on phytocannabinoids, the endogenous
cannabinoids anandamide and 2-arachidonoyl glycerol and their metabolizing and synthetic …
cannabinoids anandamide and 2-arachidonoyl glycerol and their metabolizing and synthetic …