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Advantages and limitations of current network inference methods
R De Smet, K Marchal - Nature Reviews Microbiology, 2010 - nature.com
Network inference, which is the reconstruction of biological networks from high-throughput
data, can provide valuable information about the regulation of gene expression in cells …
data, can provide valuable information about the regulation of gene expression in cells …
Demystifying the secret mission of enhancers: linking distal regulatory elements to target genes
Enhancers are short regulatory sequences bound by sequence-specific transcription factors
and play a major role in the spatiotemporal specificity of gene expression patterns in …
and play a major role in the spatiotemporal specificity of gene expression patterns in …
Target analysis by integration of transcriptome and ChIP-seq data with BETA
The combination of ChIP-seq and transcriptome analysis is a compelling approach to
unravel the regulation of gene expression. Several recently published methods combine …
unravel the regulation of gene expression. Several recently published methods combine …
[PDF][PDF] Computationally efficient convolved multiple output Gaussian processes
Recently there has been an increasing interest in regression methods that deal with multiple
outputs. This has been motivated partly by frameworks like multitask learning, multisensor …
outputs. This has been motivated partly by frameworks like multitask learning, multisensor …
Inferring gene regulatory networks from gene expression data by path consistency algorithm based on conditional mutual information
Motivation: Reconstruction of gene regulatory networks (GRNs), which explicitly represent
the causality of developmental or regulatory process, is of utmost interest and has become a …
the causality of developmental or regulatory process, is of utmost interest and has become a …
A gene regulatory network for root epidermis cell differentiation in Arabidopsis
A Bruex, RM Kainkaryam, Y Wieckowski, YH Kang… - PLoS …, 2012 - journals.plos.org
The root epidermis of Arabidopsis provides an exceptional model for studying the molecular
basis of cell fate and differentiation. To obtain a systems-level view of root epidermal cell …
basis of cell fate and differentiation. To obtain a systems-level view of root epidermal cell …
Measuring absolute RNA copy numbers at high temporal resolution reveals transcriptome kinetics in development
NDL Owens, IL Blitz, MA Lane, I Patrushev, JD Overton… - Cell reports, 2016 - cell.com
Transcript regulation is essential for cell function, and misregulation can lead to disease.
Despite technologies to survey the transcriptome, we lack a comprehensive understanding …
Despite technologies to survey the transcriptome, we lack a comprehensive understanding …
Inference of gene regulatory network based on local Bayesian networks
F Liu, SW Zhang, WF Guo, ZG Wei… - PLoS computational …, 2016 - journals.plos.org
The inference of gene regulatory networks (GRNs) from expression data can mine the direct
regulations among genes and gain deep insights into biological processes at a network …
regulations among genes and gain deep insights into biological processes at a network …
Reconstructing gene regulatory dynamics from high-dimensional single-cell snapshot data
Motivation: High-dimensional single-cell snapshot data are becoming widespread in the
systems biology community, as a mean to understand biological processes at the cellular …
systems biology community, as a mean to understand biological processes at the cellular …
Inferring gene regulatory networks using the improved Markov blanket discovery algorithm
W Liu, Y Jiang, L Peng, X Sun, W Gan, Q Zhao… - Interdisciplinary …, 2022 - Springer
Inferring gene regulatory networks (GRNs) from microarray data can help us understand the
mechanisms of life and eventually develop effective therapies. Currently, many …
mechanisms of life and eventually develop effective therapies. Currently, many …