Examining horizontal gene transfer in microbial communities

IL Brito - Nature Reviews Microbiology, 2021 - nature.com
Bacteria acquire novel DNA through horizontal gene transfer (HGT), a process that enables
an organism to rapidly adapt to changing environmental conditions, provides a competitive …

Monitoring antibiotic resistance genes in wastewater treatment: Current strategies and future challenges

AQ Nguyen, HP Vu, LN Nguyen, Q Wang… - Science of the Total …, 2021 - Elsevier
Antimicrobial resistance (AMR) is a growing threat to human and animal health. Progress in
molecular biology has revealed new and significant challenges for AMR mitigation given the …

CheckV assesses the quality and completeness of metagenome-assembled viral genomes

S Nayfach, AP Camargo, F Schulz… - Nature …, 2021 - nature.com
Millions of new viral sequences have been identified from metagenomes, but the quality and
completeness of these sequences vary considerably. Here we present CheckV, an …

[HTML][HTML] Massive expansion of human gut bacteriophage diversity

LF Camarillo-Guerrero, A Almeida, G Rangel-Pineros… - Cell, 2021 - cell.com
Bacteriophages drive evolutionary change in bacterial communities by creating gene flow
networks that fuel ecological adaptions. However, the extent of viral diversity and its …

metaFlye: scalable long-read metagenome assembly using repeat graphs

M Kolmogorov, DM Bickhart, B Behsaz, A Gurevich… - Nature …, 2020 - nature.com
Long-read sequencing technologies have substantially improved the assemblies of many
isolate bacterial genomes as compared to fragmented short-read assemblies. However …

Extensive gut virome variation and its associations with host and environmental factors in a population-level cohort

S Nishijima, N Nagata, Y Kiguchi, Y Kojima… - Nature …, 2022 - nature.com
Indigenous bacteriophage communities (virome) in the human gut have a huge impact on
the structure and function of gut bacterial communities (bacteriome), but virome variation at a …

Metagenome-assembled genome binning methods with short reads disproportionately fail for plasmids and genomic Islands

F Maguire, B Jia, KL Gray, WYV Lau… - Microbial …, 2020 - microbiologyresearch.org
Metagenomic methods enable the simultaneous characterization of microbial communities
without time-consuming and bias-inducing culturing. Metagenome-assembled genome …

Determining hosts of antibiotic resistance genes: a review of methodological advances

EW Rice, P Wang, AL Smith… - Environmental Science & …, 2020 - ACS Publications
Advancing environmental research on antibiotic resistance will require develo** better
databases of not only the occurrences of antibiotic resistance genes (ARGs) in the …

Metagenomic assembly reveals hosts and mobility of common antibiotic resistome in animal manure and commercial compost

T Qiu, L Huo, Y Guo, M Gao, G Wang, D Hu, C Li… - Environmental …, 2022 - Springer
Background Antibiotics and antibiotic resistance genes (ARGs) used in intensive animal
farming threaten human health worldwide; however, the common resistome, ARG mobility …

The third-generation sequencing challenge: novel insights for the omic sciences

C Scarano, I Veneruso, RR De Simone, G Di Bonito… - Biomolecules, 2024 - mdpi.com
The understanding of the human genome has been greatly improved by the advent of next-
generation sequencing technologies (NGS). Despite the undeniable advantages …