New advances in metabolic syndrome, from prevention to treatment: the role of diet and food

D Ambroselli, F Masciulli, E Romano, G Catanzaro… - Nutrients, 2023 - mdpi.com
The definition of metabolic syndrome (MetS) has undergone several changes over the years
due to the difficulty in establishing universal criteria for it. Underlying the disorders related to …

Uric acid in metabolic syndrome: does uric acid have a definitive role?

S Copur, A Demiray, M Kanbay - European journal of internal medicine, 2022 - Elsevier
Increased serum uric acid (SUA) levels are commonly seen in patients with metabolic
syndrome and are widely accepted as risk factors for hypertension, gout, non-alcoholic fatty …

Metabolic syndrome—A new definition and management guidelines

P Dobrowolski, A Prejbisz, A Kuryłowicz… - Arterial …, 2022 - journals.viamedica.pl
The joint position paper by Polish Society of Hypertension, Polish Society for the Treatment
of Obesity, Polish Lipid Association, Polish Association for Study of Liver, Polish Society of …

The tubular hypothesis of nephron filtration and diabetic kidney disease

V Vallon, SC Thomson - Nature Reviews Nephrology, 2020 - nature.com
Kidney size and glomerular filtration rate (GFR) often increase with the onset of diabetes,
and elevated GFR is a risk factor for the development of diabetic kidney disease …

The role of oxidative stress in hyperuricemia and xanthine oxidoreductase (XOR) inhibitors

N Liu, H Xu, Q Sun, X Yu, W Chen… - Oxidative Medicine …, 2021 - Wiley Online Library
Uric acid is the end product of purine metabolism in humans. Hyperuricemia is a metabolic
disease caused by the increased formation or reduced excretion of serum uric acid (SUA) …

The gut microbiota as a target to control hyperuricemia pathogenesis: Potential mechanisms and therapeutic strategies

J Wang, Y Chen, H Zhong, F Chen… - Critical Reviews in …, 2022 - Taylor & Francis
Hyperuricemia (HUA) is a metabolic disorder caused by abnormal uric acid (UA)
metabolism, which is a complex physiological process involving multiple organs (liver …

[HTML][HTML] Physiological functions and pathogenic potential of uric acid: A review

R El Ridi, H Tallima - Journal of advanced research, 2017 - Elsevier
Uric acid is synthesized mainly in the liver, intestines and the vascular endothelium as the
end product of an exogenous pool of purines, and endogenously from damaged, dying and …

Targeting renal glucose reabsorption to treat hyperglycaemia: the pleiotropic effects of SGLT2 inhibition

V Vallon, SC Thomson - Diabetologia, 2017 - Springer
Healthy kidneys filter∼ 160 g/day of glucose (∼ 30% of daily energy intake) under
euglycaemic conditions. To prevent valuable energy from being lost in the urine, the …

Non-alcoholic fatty liver disease and dyslipidemia: an update

N Katsiki, DP Mikhailidis, CS Mantzoros - Metabolism, 2016 - Elsevier
Non-alcoholic fatty liver (NAFLD) is the most common liver disease worldwide, progressing
from simple steatosis to necroinflammation and fibrosis (leading to non-alcoholic …

[HTML][HTML] Dietary fructose and the metabolic syndrome

MR Taskinen, CJ Packard, J Borén - Nutrients, 2019 - mdpi.com
Consumption of fructose, the sweetest of all naturally occurring carbohydrates, has
increased dramatically in the last 40 years and is today commonly used commercially in soft …