Antimicrobial peptides: A new hope in biomedical and pharmaceutical fields
Antibiotics are essential drugs used to treat pathogenic bacteria, but their prolonged use
contributes to the development and spread of drug-resistant microorganisms. Antibiotic …
contributes to the development and spread of drug-resistant microorganisms. Antibiotic …
Lessons learned from clinical trials using antimicrobial peptides (AMPs)
GS Dijksteel, MMW Ulrich, E Middelkoop… - Frontiers in …, 2021 - frontiersin.org
Antimicrobial peptides (AMPs) or host defense peptides protect the host against various
pathogens such as yeast, fungi, viruses and bacteria. AMPs also display immunomodulatory …
pathogens such as yeast, fungi, viruses and bacteria. AMPs also display immunomodulatory …
Antimicrobial peptides as therapeutic agents: Opportunities and challenges
M Mahlapuu, C Björn, J Ekblom - Critical reviews in biotechnology, 2020 - Taylor & Francis
The rapid development of microbial resistance to conventional antibiotics has accelerated
efforts to find anti-infectives with a novel mode-of-action, which are less prone to bacterial …
efforts to find anti-infectives with a novel mode-of-action, which are less prone to bacterial …
Antimicrobial peptides: diversity, mechanism of action and strategies to improve the activity and biocompatibility in vivo
Antibiotic resistance is projected as one of the greatest threats to human health in the future
and hence alternatives are being explored to combat resistance. Antimicrobial peptides …
and hence alternatives are being explored to combat resistance. Antimicrobial peptides …
Antimicrobial peptides towards clinical application: Delivery and formulation
Antimicrobial peptides hold promise to supplement small molecules antibiotics and combat
the multidrug resistant microbes. There are however technical hurdles towards the clinical …
the multidrug resistant microbes. There are however technical hurdles towards the clinical …
[HTML][HTML] Reassessing the host defense peptide landscape
Current research has demonstrated that small cationic amphipathic peptides have strong
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …
Antimicrobial peptides–Advances in development of therapeutic applications
The severe infection is becoming a significant health problem which threaten the lives of
patients and the safety and economy of society. In the way of finding new strategy …
patients and the safety and economy of society. In the way of finding new strategy …
[HTML][HTML] Antimicrobial peptides: new hope in the war against multidrug resistance
The discovery of antibiotics marked a golden age in the revolution of human medicine.
However, decades later, bacterial infections remain a global healthcare threat, and a return …
However, decades later, bacterial infections remain a global healthcare threat, and a return …
[HTML][HTML] Advancements, challenges and future perspectives on peptide-based drugs: Focus on antimicrobial peptides
X Luo, H Chen, Y Song, Z Qin, L Xu, N He, Y Tan… - European Journal of …, 2023 - Elsevier
Among other health related issues, the rising concerns on drug resistance led to look for
alternative pharmaceutical drugs that are effective both against infectious and noninfectious …
alternative pharmaceutical drugs that are effective both against infectious and noninfectious …
3D printing for bone repair: Coupling infection therapy and defect regeneration
The treatment of infected bone defects is a major clinical challenge, which requires the
development of scaffolds to simultaneously eliminate infection and provide a suitable …
development of scaffolds to simultaneously eliminate infection and provide a suitable …