Ulcerative colitis in adults: a review

B Gros, GG Kaplan - Jama, 2023‏ - jamanetwork.com
Importance Ulcerative colitis (UC) is a chronic inflammatory condition of the colon, with a
prevalence exceeding 400 per 100 000 in North America. Individuals with UC have a lower …

Strategies for targeting cytokines in inflammatory bowel disease

MF Neurath - Nature Reviews Immunology, 2024‏ - nature.com
Cytokines produced by immune cells contribute to the development and perpetuation of
inflammatory bowel disease (IBD), namely Crohn's disease and ulcerative colitis, by …

ECCO guidelines on therapeutics in ulcerative colitis: medical treatment

T Raine, S Bonovas, J Burisch… - Journal of Crohn's …, 2022‏ - academic.oup.com
Ulcerative colitis [UC] is a chronic inflammatory bowel disease [IBD] characterised by colonic
inflammation extending to a variable extent from the rectum. Care of the patient with UC …

STRIDE-II: an update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD …

D Turner, A Ricciuto, A Lewis, F D'amico, J Dhaliwal… - Gastroenterology, 2021‏ - Elsevier
Background The Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE)
initiative of the International Organization for the Study of Inflammatory Bowel Diseases …

Efficacy and safety of biologics and small molecule drugs for patients with moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis

JS Lasa, PA Olivera, S Danese… - The Lancet …, 2022‏ - thelancet.com
Background There is a growing armamentarium for the treatment of moderate-to-severe
ulcerative colitis. We aimed to compare the relative efficacy and safety of biologics and small …

Evidence-based clinical practice guidelines for inflammatory bowel disease 2020

H Nakase, M Uchino, S Shinzaki, M Matsuura… - Journal of …, 2021‏ - Springer
Inflammatory bowel disease (IBD) is a general term for chronic or remitting/relapsing
inflammatory diseases of the intestinal tract and generally refers to ulcerative colitis (UC) …

Newer biologic and small-molecule therapies for inflammatory bowel disease

DC Baumgart, C Le Berre - New England Journal of Medicine, 2021‏ - Mass Medical Soc
Newer Biologic and Small-Molecule Therapies for IBD There is still no cure for inflammatory
bowel disease. This review covers newer treatments that reflect our understanding of the …

Crohn's disease

G Roda, S Chien Ng, PG Kotze, M Argollo… - Nature Reviews …, 2020‏ - nature.com
Crohn's disease is an inflammatory bowel disease that is characterized by chronic
inflammation of any part of the gastrointestinal tract, has a progressive and destructive …

Approach to the management of recently diagnosed inflammatory bowel disease patients: a user's guide for adult and pediatric gastroenterologists

M Agrawal, EA Spencer, JF Colombel, RC Ungaro - Gastroenterology, 2021‏ - Elsevier
Inflammatory bowel diseases (IBDs), including Crohn's disease and ulcerative colitis, are
chronic, progressive, immune-mediated diseases of adults and children that have no cure …

Ulcerative colitis—diagnostic and therapeutic algorithms

T Kucharzik, S Koletzko… - Deutsches Ärzteblatt …, 2020‏ - pmc.ncbi.nlm.nih.gov
Background Ulcerative colitis is a chronic inflammatory bowel disease with an estimated 150
000 patients in Germany alone. Methods This review is based on publications about current …