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Neural circuits regulating visceral pain
X Chang, H Zhang, S Chen - Communications Biology, 2024 - nature.com
Visceral hypersensitivity, a common clinical manifestation of irritable bowel syndrome, may
contribute to the development of chronic visceral pain, which is a major challenge for both …
contribute to the development of chronic visceral pain, which is a major challenge for both …
Claustrum neurons projecting to the anterior cingulate restrict engagement during sleep and behavior
The claustrum has been linked to attention and sleep. We hypothesized that this reflects a
shared function, determining responsiveness to stimuli, which spans the axis of …
shared function, determining responsiveness to stimuli, which spans the axis of …
Claustrum and dorsal endopiriform cortex complex cell-identity is determined by Nurr1 and regulates hallucinogenic-like states in mice
The Claustrum/dorsal endopiriform cortex complex (CLA) is an enigmatic brain region with
extensive glutamatergic projections to multiple cortical areas. The transcription factor Nurr1 …
extensive glutamatergic projections to multiple cortical areas. The transcription factor Nurr1 …
Updating functional brain units: insights far beyond Luria
This paper reviews Luria's model of the three functional units of the brain. To meet this
objective, several issues were reviewed: the theory of functional systems and the …
objective, several issues were reviewed: the theory of functional systems and the …
Pain-induced adaptations in the claustro-cingulate pathway
Persistent pain is a prevalent medical concern correlating with a hyperexcitable anterior
cingulate cortex (ACC). Its activity is modulated by inputs from several brain regions, but the …
cingulate cortex (ACC). Its activity is modulated by inputs from several brain regions, but the …
Brain-state-dependent constraints on claustrocortical communication and function
Neural activity in the claustrum has been associated with a range of vigilance states, yet the
activity patterns and efficacy of synaptic communication of identified claustrum neurons have …
activity patterns and efficacy of synaptic communication of identified claustrum neurons have …
Pathological claustrum activity drives aberrant cognitive network processing in human chronic pain
Aberrant cognitive network activity and cognitive deficits are established features of chronic
pain. However, the nature of cognitive network alterations associated with chronic pain and …
pain. However, the nature of cognitive network alterations associated with chronic pain and …
A simple and reliable method for claustrum localization across age in mice
T Shaker, GJ Dagpa, V Cattaud, BA Marriott, M Sultan… - Molecular Brain, 2024 - Springer
The anatomical organization of the rodent claustrum remains obscure due to lack of clear
borders that distinguish it from neighboring forebrain structures. Defining what constitutes …
borders that distinguish it from neighboring forebrain structures. Defining what constitutes …
Decoupling of cortical activity from behavioral state following administration of the classic psychedelic DOI
Administration or consumption of classic psychedelics (CPs) leads to profound changes in
experience which are often described as highly novel and meaningful. They have shown …
experience which are often described as highly novel and meaningful. They have shown …
Involvement of the claustrum in the cortico-basal ganglia circuitry: connectional study in the non-human primate
The claustrum is an ancient telencephalic subcortical structure displaying extensive,
reciprocal connections with much of the cortex and receiving projections from thalamus …
reciprocal connections with much of the cortex and receiving projections from thalamus …