Host immunity and immunization strategies for Clostridioides difficile infection

F Naz, WA Petri - Clinical Microbiology Reviews, 2023 - Am Soc Microbiol
Clostridioides difficile infection (CDI) represents a significant challenge to public health. C.
difficile-associated mortality and morbidity have led the US CDC to designate it as an urgent …

Depletion of butyrate-producing microbes of the Firmicutes predicts nonresponse to FMT therapy in patients with recurrent Clostridium difficile infection

H Tian, J Cui, C Ye, J Zhao, B Yang, Y Xu, S Ji… - Gut …, 2023 - Taylor & Francis
Approximately 10% of individuals diagnosed with Clostridium difficile infection (CDI) show
the resistance to fecal microbiota transplantation (FMT), with the underlying mechanisms …

Response under pressure: deploying emerging technologies to understand B-cell-mediated immunity in COVID-19

MC Woodruff, DC Nguyen, CE Faliti, AS Saini… - Nature …, 2022 - nature.com
Critical technological advances have enabled the rapid investigations into the immune
responses elicited by SARS-CoV-2, the pathogen responsible for the COVID-19 pandemic …

Circulating antibody-secreting cells are a biomarker for early diagnosis in patients with Lyme disease

NS Haddad, S Nozick, S Ohanian, R Smith, S Elias… - PloS one, 2023 - journals.plos.org
Background Diagnostic immunoassays for Lyme disease have several limitations including:
1) not all patients seroconvert; 2) seroconversion occurs later than symptom onset; and 3) …

[HTML][HTML] Gene Expression Dysregulation in Whole Blood of Patients with Clostridioides difficile Infection

M Tsakiroglou, A Evans… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Clostridioides difficile (C. difficile) is a global threat and has significant implications for
individuals and health care systems. Little is known about host molecular mechanisms and …

MENSA, a Media Enriched with Newly Synthesized Antibodies, to Identify SARS-CoV-2 Persistence and Latent Viral Reactivation in Long-COVID

NS Haddad, A Morrison-Porter, H Quehl, V Capric… - medRxiv, 2024 - pmc.ncbi.nlm.nih.gov
Post-acute sequelae of SARS-CoV-2 (SARS2) infection (PASC) is a heterogeneous
condition, but the main viral drivers are unknown. Here, we use MENSA, Media Enriched …

[HTML][HTML] Clostridioides difficile: название новое, проблемы диагностики и терапии прежние

СМ Захаренко - Альманах клинической медицины, 2022 - cyberleninka.ru
Clostridium difficile была реклассифицирована в 2016 г. и получила новое
наименование Clostridioides difficile. В 2021-2022 гг. внесены изменения в основные …

Clostridioides difficile–a new name, the old problems with diagnosis and treatment

SM Zakharenko - Almanac of Clinical Medicine, 2022 - almclinmed.ru
Clostridium difficile was reclassified in 2016 under a new name of Clostridioides difficile. In
2021 to 2022, some changes were implemented into the main clinical guidelines on the …

MENSA, a Media Enriched with Newly Synthesized Antibodies, to Identify SARS-CoV-2 Persistence and Latent Viral Reactivation in Long-COVID

F Lee, N Haddad, A Morrison-Porter, H Quehl, V Capric… - 2024 - researchsquare.com
Post-acute sequelae of SARS-CoV-2 (SARS2) infection (PASC) is a heterogeneous
condition, but the main viral drivers are unknown. Here, we use MENSA, Media Enriched …

[BOOK][B] Identifying Immune Correlates of Protection Against Clostridioides difficile Infection and the Development of an Optimized C. difficile Toxin DNA Vaccine for …

MR Bell - 2023 - search.proquest.com
Clostridioides difficile is the causative agent of C. difficile infection (CDI) which is an enteric
infection that leads to severe diarrhea and intestinal inflammation and is the leading …