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Nanocarrier‐mediated cytosolic delivery of biopharmaceuticals
Biopharmaceuticals have emerged to play a vital role in disease treatment and have shown
promise in the rapidly expanding pharmaceutical market due to their high specificity and …
promise in the rapidly expanding pharmaceutical market due to their high specificity and …
Impact of nanoparticles on amyloid peptide and protein aggregation: a review with a focus on gold nanoparticles
Society is increasingly exposed to nanoparticles as they are ubiquitous in nature and
introduced as man-made air pollutants and as functional ingredients in cosmetic products as …
introduced as man-made air pollutants and as functional ingredients in cosmetic products as …
COVID-19 diagnosis by SARS-CoV-2 Spike protein detection in saliva using an ultrasensitive magneto-assay based on disposable electrochemical sensor
The outbreak of the COVID-19 pandemic, caused by Severe Acute Respiratory Syndrome of
Coronavirus 2 (SARS-CoV-2), has fueled the search for diagnostic tests aiming at the control …
Coronavirus 2 (SARS-CoV-2), has fueled the search for diagnostic tests aiming at the control …
Melimine-modified 3D-printed polycaprolactone scaffolds for the prevention of biofilm-related biomaterial infections
Biomaterial-associated infections are one of the major causes of implant failure. These
infections result from persistent bacteria that have adhered to the biomaterial surface before …
infections result from persistent bacteria that have adhered to the biomaterial surface before …
[HTML][HTML] Unravelling the physicochemical and antimicrobial mechanisms of human serum albumin/tannic acid coatings for medical-grade polycaprolactone scaffolds
Biofilm-related biomaterial infections are notoriously challenging to treat and can lead to
chronic infection and persisting inflammation. To date, a large body of research can be …
chronic infection and persisting inflammation. To date, a large body of research can be …
Peptide Self‐Assembly into Amyloid Fibrils at Hard and Soft Interfaces—From Corona Formation to Membrane Activity
Peptides and proteins are exposed to a variety of interfaces in a physiological environment,
such as cell membranes, protein nanoparticles (NPs), or viruses. These interfaces have a …
such as cell membranes, protein nanoparticles (NPs), or viruses. These interfaces have a …
Dual-stage blue-light-guided membrane and DNA-targeted photodynamic inactivation using octyl gallate for ultraefficient eradication of planktonic bacteria and sessile …
Y Shi, S Lin, W Chen, L Jiang, Q Gu, D Li… - Journal of Agricultural …, 2022 - ACS Publications
This study aimed to investigate the synergistic bactericidal activity and mechanism of dual-
stage light-guided membrane and DNA-targeted photodynamic inactivation (PDI) by the …
stage light-guided membrane and DNA-targeted photodynamic inactivation (PDI) by the …
Lipid oxidation controls peptide self-assembly near membranes through a surface attraction mechanism
T John, S Piantavigna, TJA Dealey, B Abel… - Chemical …, 2023 - pubs.rsc.org
The self-assembly of peptides into supramolecular structures has been linked to
neurodegenerative diseases but has also been observed in functional roles. Peptides are …
neurodegenerative diseases but has also been observed in functional roles. Peptides are …
Adsorption of amyloidogenic peptides to functionalized surfaces is biased by charge and hydrophilicity
Surfaces are abundant in living systems, such as in the form of cellular membranes, and
govern many biological processes. In this study, the adsorption of the amyloidogenic model …
govern many biological processes. In this study, the adsorption of the amyloidogenic model …
[HTML][HTML] Biophysical characterization of LTX-315 anticancer peptide interactions with model membrane platforms: effect of membrane surface charge
LTX-315 is a clinical-stage, anticancer peptide therapeutic that disrupts cancer cell
membranes. Existing mechanistic knowledge about LTX-315 has been obtained from cell …
membranes. Existing mechanistic knowledge about LTX-315 has been obtained from cell …