Purpose Functional status and chronic health status are important baseline characteristics of
critically ill patients. The assessment of frailty on admission to the intensive care unit (ICU) …

Traditional approaches to clinical risk assessment utilize age as a marker of increased
vulnerability to stress. Relatively recent advancements in the study of aging have led to the …

The improvement of life quality and medical advances has resulted in increased life
expectancy. Despite this, health status commonly worsens in the last years of life. Frailty is …

Aging frailty is a complex geriatric syndrome that becomes more prevalent with advancing
age. It constitutes a major health problem due to frequent adverse outcomes. Frailty is …

Frailty is a complex geriatric syndrome associated with biological vulnerability to stressors
and decreased physiological reserve. Its etiology and pathogenesis are not completely …

Ferroptosis is a distinctive form of iron-dependent necrotic cell death, characterized by
excessive lipid peroxidation on cellular membranes and compromised cellular antioxidant …

Purpose To describe pre-ICU frailty in critically ill patients using the Clinical Frailty Scale
(CFS). Methods We included patients≥ 18 years admitted to 2 ICUs in Hamilton, Canada …

Frailty is a syndrome characterized by the decline in the physiologic reserve and function of
several systems, leading to increased vulnerability and adverse health outcomes. While …

Abstract Frailty and Biological Age are two closely related concepts; however, frailty is a
multisystem geriatric syndrome that applies to elderly subjects, whereas biological age is a …

Anti-aging research has become critical since the elderly population is increasing
dramatically in this era. With the establishment of frailty phenotype and frailty index, the …