Triazoles and their derivatives: Chemistry, synthesis, and therapeutic applications

MM Matin, P Matin, MR Rahman… - Frontiers in molecular …, 2022 - frontiersin.org
Among the nitrogen-containing heterocyclic compounds, triazoles emerge with superior
pharmacological applications. Structurally, there are two types of five-membered triazoles: 1 …

Ionic liquids for green synthesis of 1, 2, 3-triazoles: a systematic review

A Kumar, V Kumar, P Singh, RK Tittal, K Lal - Green Chemistry, 2024 - pubs.rsc.org
The exponentially increasing use of hazardous traditional organic solvents and catalysts for
more accessible synthesis of important heterocycles useful for humankind in various fields …

Recent progress in catalytic synthesis of 1, 2, 3-triazoles

A De Nino, L Maiuolo, P Costanzo, V Algieri, A Jiritano… - Catalysts, 2021 - mdpi.com
1, 2, 3-triazoles represent a functional heterocyclic core that has been at the center of
modern organic chemistry since the beginning of click chemistry. Being a versatile …

Recent progress on synthesis of functionalized 1, 5-disubstituted triazoles

MK Jaiswal, A Gupta, FJ Ansari… - Current Organic …, 2024 - benthamdirect.com
Immediately after the invention of 'Click Chemistry'in 2002, the regioselective 1, 2, 3-triazole
scaffolds resulted from respective organic azides and terminal alkynes under Cu (I) catalysis …

Metal-free syntheses of N-functionalized and NH-1, 2, 3-triazoles: an update on recent developments

T Opsomer, W Dehaen - Chemical Communications, 2021 - pubs.rsc.org
An overview of the latest developments in the metal-free synthesis of non-benzo-fused N-
functionalized and NH-1, 2, 3-triazoles is provided in this feature article. Synthetic studies …

[HTML][HTML] Green synthesis of privileged benzimidazole scaffolds using active deep eutectic solvent

ML Di Gioia, R Cassano, P Costanzo, N Herrera Cano… - Molecules, 2019 - mdpi.com
The exploitation and use of alternative synthetic methods, in the face of classical procedures
that do not conform to the ethics of green chemistry, represent an ever-present problem in …

[HTML][HTML] Azides in the synthesis of various heterocycles

AEAA Nayl, AA Aly, WAA Arafa, IM Ahmed… - Molecules, 2022 - mdpi.com
In this review, we focus on some interesting and recent examples of various applications of
organic azides such as their intermolecular or intramolecular, under thermal, catalyzed, or …

Recent developments on 1, 3-dipolar cycloaddition reactions by catalysis in green solvents

L Maiuolo, V Algieri, F Olivito, A De Nino - Catalysts, 2020 - mdpi.com
The use of eco-compatible synthetic procedures in organic reactions and, in particular, in 1,
3-dipolar cycloaddition reactions, has recently received a great deal of attention and …

Sustainable click reactions: use of greener reaction media in the synthesis of 1, 2, 3-triazoles

LA Martinho, CKZ Andrade - Tetrahedron, 2024 - Elsevier
Heterocyclic compounds are widely found in nature, more specifically, five-or six-membered
rings nitrogen heterocycles are important in the synthesis of biologically active compounds …

Emerging approaches for synthesis of 1, 2, 3-triazole derivatives. A review

S Jaiswal, M Devi, N Sharma, K Rathi… - Organic Preparations …, 2022 - Taylor & Francis
Triazoles are privileged compounds that have received considerable attention from organic
chemists worldwide due to their role in drug development. Triazole based hybrids have also …