Cellular mechanotransduction in health and diseases: from molecular mechanism to therapeutic targets

X Di, X Gao, L Peng, J Ai, X **, S Qi, H Li… - Signal transduction and …, 2023 - nature.com
Cellular mechanotransduction, a critical regulator of numerous biological processes, is the
conversion from mechanical signals to biochemical signals regarding cell activities and …

Biomechanics of chondrocytes and chondrons in healthy conditions and osteoarthritis: a review of the mechanical characterisations at the microscale

S Pettenuzzo, A Arduino, E Belluzzi, A Pozzuoli… - Biomedicines, 2023 - mdpi.com
Biomechanical studies are expanding across a variety of fields, from biomedicine to
biomedical engineering. From the molecular to the system level, mechanical stimuli are …

Osteotomy around the knee: the surgical treatment of osteoarthritis

H Peng, A Ou, X Huang, C Wang, L Wang… - Orthopaedic …, 2021 - Wiley Online Library
Osteoarthritis causes joint pain and functional disorder, of which knee osteoarthritis is the
most common. Nowadays, clinically effective treatments mainly include conservative …

Medial compartment decompression by fibular osteotomy to treat medial compartment knee osteoarthritis: a pilot study

ZY Yang, W Chen, CX Li, J Wang, DC Shao… - …, 2015 - journals.healio.com
Compared with high tibial osteotomy and total knee arthroplasty, the authors found a simpler
surgical procedure, partial fibular osteotomy, could effectively relieve knee pain and also …

Senescent cells and the incidence of age‐related diseases

I Katzir, M Adler, O Karin, N Mendelsohn‐Cohen… - Aging …, 2021 - Wiley Online Library
Age‐related diseases such as cancer, cardiovascular disease, kidney failure, and
osteoarthritis have universal features: Their incidence rises exponentially with age with a …

Diurnal variations in articular cartilage thickness and strain in the human knee

JL Coleman, MR Widmyer, HA Leddy, GM Utturkar… - Journal of …, 2013 - Elsevier
Due to the biphasic viscoelastic nature of cartilage, joint loading may result in deformations
that require times on the order of hours to fully recover. Thus, cartilaginous tissues may …

The effect of intra‐articular injection of autologous bone marrow stem cells on pain and knee function in patients with osteoarthritis

D Garay‐Mendoza, L Villarreal‐Martínez… - … journal of rheumatic …, 2018 - Wiley Online Library
Aim Management of osteoarthritis (OA) is basically symptomatic. Recently, stem cells (SC)
have been used in the search for an optimum treatment. We decided to conduct a controlled …

[HTML][HTML] Aerobic exercise training and low-level laser therapy modulate inflammatory response and degenerative process in an experimental model of knee …

L Assis, LP Milares, T Almeida, C Tim, A Magri… - Osteoarthritis and …, 2016 - Elsevier
Objective The aim of this study was to evaluate the effects of an aerobic exercise training
and low-level laser therapy (LLLT)(associated or not) on degenerative modifications and …

Management of knee osteoarthritis. Current status and future trends

M Ondrésik, FR Azevedo Maia… - Biotechnology and …, 2017 - Wiley Online Library
Osteoarthritis (OA) affects a large number of the population, and its incidence is showing a
growing trend with the increasing life span. OA is the most prevalent joint condition …

The use of oral appliances in the management of temporomandibular disorders

CS Greene, HF Menchel - Oral and …, 2018 - oralmaxsurgery.theclinics.com
There are few topics concerning temporomandibular disorders (TMDs) that elicit more
disagreement and controversy than the use of oral appliances (OAs) in treating these …