Depression is a heterogeneous and etiologically complex psychiatric syndrome, not a
unitary disease entity, encompassing a broad spectrum of psychopathology arising from …

Phosphorylation is one of the quickest post-translational modifications that controls
downstream signaling pathways regulating processes like cell proliferation, survival, and …

Combination of CDK4/6 inhibitors and endocrine therapy improves clinical outcome in
advanced oestrogen receptor (ER)-positive breast cancer, however relapse is inevitable …

Mass‐spectrometry based bottom‐up proteomics is the main method to analyze proteomes
comprehensively and the rapid evolution of instrumentation and data analysis has made the …

The ubiquitous pathogen Toxoplasma gondii has a complex lifestyle with different metabolic
activities at different stages that are intimately linked to the parasitic environments. Here we …

Gain of function LRRK2‐G2019S is the most frequent mutation found in familial and
sporadic Parkinson's disease. It is expected therefore that understanding the cellular …

Large-scale phosphoproteome profiling using mass spectrometry (MS) provides functional
insight that is crucial for disease biology and drug discovery. However, extracting biological …

Modern agricultural systems are directly threatened by global climate change and the
resulting freshwater crisis. A considerable challenge in the coming years will be to develop …

ProteoArk is a web-based tool that offers a range of computational pipelines for
comprehensive analysis and visualization of mass spectrometry-based proteomics data. The …

Iron-carbohydrate complexes are widely used to treat iron deficiencies. Macrophages play a
crucial role in the uptake and fate of these nanomedicines, however, how complexed iron …