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Inflammation‐related mechanisms in chronic kidney disease prediction, progression, and outcome
S Mihai, E Codrici, ID Popescu… - Journal of …, 2018 - Wiley Online Library
Persistent, low‐grade inflammation is now considered a hallmark feature of chronic kidney
disease (CKD), being involved in the development of all‐cause mortality of these patients …
disease (CKD), being involved in the development of all‐cause mortality of these patients …
Cardiac surgery-associated acute kidney injury: risk factors, pathophysiology and treatment
Y Wang, R Bellomo - Nature Reviews Nephrology, 2017 - nature.com
Cardiac surgery-associated acute kidney injury (CSA-AKI) is the most common clinically
important complication in adult patients undergoing open heart surgery, and is associated …
important complication in adult patients undergoing open heart surgery, and is associated …
Comparative accuracy of biomarkers for the prediction of hospital-acquired acute kidney injury: a systematic review and meta-analysis
Background Several biomarkers have been proposed to predict the occurrence of acute
kidney injury (AKI); however, their efficacy varies between different trials. The aim of this …
kidney injury (AKI); however, their efficacy varies between different trials. The aim of this …
Biomarkers of acute and chronic kidney disease
WR Zhang, CR Parikh - Annual review of physiology, 2019 - annualreviews.org
The current unidimensional paradigm of kidney disease detection is incompatible with the
complexity and heterogeneity of renal pathology. The diagnosis of kidney disease has …
complexity and heterogeneity of renal pathology. The diagnosis of kidney disease has …
Biomarkers in acute kidney injury–pathophysiological basis and clinical performance
Various biomarkers of acute kidney injury (AKI) have been discovered and characterized in
the recent past. These molecules can be detected in urine or blood and signify structural …
the recent past. These molecules can be detected in urine or blood and signify structural …
Proficient novel biomarkers guide early detection of acute kidney injury: a review
The definition of acute kidney injury (AKI), despite improvements in criteria, continues to be
based on the level of serum creatinine and urinary output that do not specifically indicate …
based on the level of serum creatinine and urinary output that do not specifically indicate …
Acute kidney injury
Acute kidney injury (AKI) is defined by a rapid increase in serum creatinine, decrease in
urine output, or both. AKI occurs in approximately 10–15% of patients admitted to hospital …
urine output, or both. AKI occurs in approximately 10–15% of patients admitted to hospital …
Biomarkers of AKI: a review of mechanistic relevance and potential therapeutic implications
JL Alge, JM Arthur - Clinical journal of the American Society of …, 2015 - journals.lww.com
AKI is a common clinical condition associated with a number of adverse outcomes. More
timely diagnosis would allow for earlier intervention and could improve patient outcomes …
timely diagnosis would allow for earlier intervention and could improve patient outcomes …
[HTML][HTML] Urinary, plasma, and serum biomarkers' utility for predicting acute kidney injury associated with cardiac surgery in adults: a meta-analysis
Background Early accurate detection of acute kidney injury (AKI) occurring after cardiac
surgery may improve morbidity and mortality. Although several novel biomarkers have been …
surgery may improve morbidity and mortality. Although several novel biomarkers have been …
A basic science view of acute kidney injury biomarkers
JR Charlton, D Portilla, MD Okusa - Nephrology Dialysis …, 2014 - academic.oup.com
Over the last decade, significant progress has been made in the identification and validation
of novel biomarkers as well as refinements in the use of serum creatinine as a marker of …
of novel biomarkers as well as refinements in the use of serum creatinine as a marker of …