Codon usage bias
Codon usage bias is the preferential or non-random use of synonymous codons, a
ubiquitous phenomenon observed in bacteria, plants and animals. Different species have …
ubiquitous phenomenon observed in bacteria, plants and animals. Different species have …
Acyl-CoA: diacylglycerol acyltransferase: molecular biology, biochemistry and biotechnology
Triacylglycerol (TG) is a storage lipid which serves as an energy reservoir and a source of
signalling molecules and substrates for membrane biogenesis. TG is essential for many …
signalling molecules and substrates for membrane biogenesis. TG is essential for many …
Expression pattern and, surprisingly, gene length shape codon usage in Caenorhabditis, Drosophila, and Arabidopsis
L Duret, D Mouchiroud - Proceedings of the National …, 1999 - National Acad Sciences
We measured the expression pattern and analyzed codon usage in 8,133, 1,550, and 2,917
genes, respectively, from Caenorhabditis elegans, Drosophila melanogaster, and …
genes, respectively, from Caenorhabditis elegans, Drosophila melanogaster, and …
Codon usage: nature's roadmap to expression and folding of proteins
E Angov - Biotechnology journal, 2011 - Wiley Online Library
Biomedical and biotechnological research relies on processes leading to the successful
expression and production of key biological products. High‐quality proteins are required for …
expression and production of key biological products. High‐quality proteins are required for …
Ribosome and transcript copy numbers, polysome occupancy and enzyme dynamics in Arabidopsis
Plants are exposed to continual changes in the environment. The daily alternation between
light and darkness results in massive recurring changes in the carbon budget, and leads to …
light and darkness results in massive recurring changes in the carbon budget, and leads to …
Gene expression and molecular evolution
H Akashi - Current Opinion in Genetics & Development, 2001 - Elsevier
The combination of complete genome sequence information and estimates of mRNA
abundances have begun to reveal causes of both silent and protein sequence evolution …
abundances have begun to reveal causes of both silent and protein sequence evolution …
Modulation of poliovirus replicative fitness in HeLa cells by deoptimization of synonymous codon usage in the capsid region
CC Burns, J Shaw, R Campagnoli, J Jorba… - Journal of …, 2006 - Am Soc Microbiol
We replaced degenerate codons for nine amino acids within the capsid region of the Sabin
type 2 oral poliovirus vaccine strain with corresponding nonpreferred synonymous codons …
type 2 oral poliovirus vaccine strain with corresponding nonpreferred synonymous codons …
The effects of Hill-Robertson interference between weakly selected mutations on patterns of molecular evolution and variation
GAT McVean, B Charlesworth - Genetics, 2000 - academic.oup.com
Associations between selected alleles and the genetic backgrounds on which they are
found can reduce the efficacy of selection. We consider the extent to which such …
found can reduce the efficacy of selection. We consider the extent to which such …
DNA helix: the importance of being GC‐rich
AE Vinogradov - Nucleic acids research, 2003 - academic.oup.com
A new explanation for the emergence of heavy (GC‐rich) isochores is proposed, based on
the study of thermostability, bendability, ability to B–Z transition and curvature of the DNA …
the study of thermostability, bendability, ability to B–Z transition and curvature of the DNA …
Translational selection and molecular evolution
H Akashi, A Eyre-Walker - Current opinion in genetics & development, 1998 - Elsevier
Translational selection and molecular evolution Page 1 688 Translational selection and
molecular evolution Hiroshi Akashi* and Adam Eyre-Walker? An interplay among …
molecular evolution Hiroshi Akashi* and Adam Eyre-Walker? An interplay among …