The control of translation is increasingly recognized as a major factor in determining protein
levels in the cell. The ribosome—the cellular machine that mediates protein synthesis—is …

The malaria parasite Plasmodium spp. varies the expression profile of its genes depending
on the host it resides in and its developmental stage. Virtually all messenger RNA (mRNA) is …

There is mounting evidence that the ribosome is not a static translation machinery, but a cell-
specific, adaptive system. Ribosomal variations have mostly been studied at the protein …

Malaria remains a major global health burden, causing over 247 million cases and 619,000
deaths in 2021 [1]. This disease is caused by eukaryotic, apicomplexan parasites in the …

Background Plasmodium species feature only four to eight nuclear ribosomal units on
different chromosomes, which are assumed to evolve independently according to a birth …

Ribosomes, in general, are viewed as constitutive macromolecular machines where protein
synthesis takes place; however, this view has been recently challenged, supporting the …

Genetic map** has been widely employed to search for genes linked to phenotypes/traits
of interest. Because of the ease of maintaining rodent malaria parasites in laboratory mice …

Infection of mice with strains of Plasmodium yoelii parasites can result in different pathology,
but molecular mechanisms to explain this variation are unclear. Here we show that a P …

Malaria is caused by unicellular apicomplexan parasites of the genus Plasmodium, which
includes the major human parasite Plasmodium falciparum. The complex cycle of the …

Most mammalian Plasmodium species possess distinct 18S ribosomal RNA (rRNA) gene
copies, which are differentially expressed in vertebrate hosts and mosquito vectors …