Osteoporosis and fractures in women: the burden of disease

M Lorentzon, H Johansson, NC Harvey, E Liu… - …, 2022 - Taylor & Francis
Osteoporosis is a disease characterized by impaired bone microarchitecture and reduced
bone mineral density (BMD) resulting in bone fragility and increased risk of fracture. In …

Bone modeling and remodeling: potential as therapeutic targets for the treatment of osteoporosis

B Langdahl, S Ferrari… - Therapeutic advances in …, 2016 - journals.sagepub.com
The adult skeleton is renewed by remodeling throughout life. Bone remodeling is a process
where osteoclasts and osteoblasts work sequentially in the same bone remodeling unit …

Mind the (treatment) gap: a global perspective on current and future strategies for prevention of fragility fractures

NCW Harvey, EV McCloskey, PJ Mitchell… - Osteoporosis …, 2017 - Springer
This narrative review considers the key challenges facing healthcare professionals and
policymakers responsible for providing care to populations in relation to bone health. These …

Bioactive poly (methyl methacrylate) bone cement for the treatment of osteoporotic vertebral compression fractures

J Zhu, S Yang, K Cai, S Wang, Z Qiu, J Huang… - …, 2020 - pmc.ncbi.nlm.nih.gov
Rationale: Poly (methyl methacrylate)(PMMA) bone cement is one of the most commonly
used biomaterials for augmenting/stabilizing osteoporosis-induced vertebral compression …

Orthogeriatric co-management–managing frailty as well as fragility

G Pioli, C Bendini, P Pignedoli, A Giusti, D Marsh - Injury, 2018 - Elsevier
A high proportion of patients with fragility fracture, mainly hip fracture, have a variable
degree of comorbidity and show some degree of dependence in basic or more complex …

Herba Epimedii: an ancient Chinese herbal medicine in the prevention and treatment of osteoporosis

L Wang, Y Li, Y Guo, R Ma, M Fu, J Niu… - Current …, 2016 - benthamdirect.com
Herba Epimedii (HEP) known as YinYangHuo in Chinese is the dried leaf of the
Epimediium, and has been historically used in combination with other herbs to treat skeletal …

Teriparatide in patients with osteoporosis and type 2 diabetes

AV Schwartz, I Pavo, J Alam, DP Disch, D Schuster… - Bone, 2016 - Elsevier
Despite evidence for higher fracture risk, clinical effects of osteoporosis treatments in type 2
diabetes (T2D) are largely unknown. Post hoc analyses of the DANCE observational study …

A survey of outcomes and management of patients post fragility fractures in China

O Wang, Y Hu, S Gong, Q Xue, Z Deng, L Wang… - Osteoporosis …, 2015 - Springer
We found that the fragility hip and vertebral fractures caused excess mortality rates in this
Chinese female population, which was unexpectedly lower than those in western countries …

Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin

C Wu, EB Rankin, L Castellini… - Genes & …, 2015 - genesdev.cshlp.org
The bone microenvironment is composed of niches that house cells across variable oxygen
tensions. However, the contribution of oxygen gradients in regulating bone and blood …

Correlation between bone density, bone metabolism markers with lipid metabolism markers and body mass index

H Han, R Li, D Fu, H Zhou, Z Zhan, Y Wu… - BMC Musculoskeletal …, 2024 - Springer
Purpose We aimed to explore the relationship between bone mineral density (BMD), bone
metabolism markers, and blood lipid-related indicators, body mass index (BMI) in elderly …