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Giant cells around bone biomaterials: Osteoclasts or multi-nucleated giant cells?
Recently accumulating evidence has put into question the role of large multinucleated giant
cells (MNGCs) around bone biomaterials. While cells derived from the monocyte …
cells (MNGCs) around bone biomaterials. While cells derived from the monocyte …
[HTML][HTML] In vivo cellular reactions to different biomaterials—Physiological and pathological aspects and their consequences
S Al-Maawi, A Orlowska, R Sader, CJ Kirkpatrick… - Seminars in …, 2017 - Elsevier
Biomaterials are widely used in guided bone regeneration (GBR) and guided tissue
regeneration (GTR). After application, there is an interaction between the host immune …
regeneration (GTR). After application, there is an interaction between the host immune …
[HTML][HTML] Analysis of the in vitro degradation and the in vivo tissue response to bi-layered 3D-printed scaffolds combining PLA and biphasic PLA/bioglass components …
The aim of the present study was the in vitro and in vivo analysis of a bi-layered 3D-printed
scaffold combining a PLA layer and a biphasic PLA/bioglass G5 layer for regeneration of …
scaffold combining a PLA layer and a biphasic PLA/bioglass G5 layer for regeneration of …
A low-speed centrifugation concept leads to cell accumulation and vascularization of solid platelet-rich fibrin: an experimental study in vivo
A Kubesch, M Barbeck, S Al-Maawi, A Orlowska… - Platelets, 2019 - Taylor & Francis
Platelet-rich fibrin (PRF) is generated from the patients' own venous blood by a single
centrifugation step without the additional use of anticoagulants. Based on the previously …
centrifugation step without the additional use of anticoagulants. Based on the previously …
Multinucleated giant cells in the implant bed of bone substitutes are foreign body giant cells—New insights into the material‐mediated healing process
M Barbeck, P Booms, R Unger… - … Research Part A, 2017 - Wiley Online Library
In addition to macrophages, multinucleated giant cells (MNGCs) are involved in the tissue
reaction to a variety of biomaterials. Especially in the case of bone substitute materials it has …
reaction to a variety of biomaterials. Especially in the case of bone substitute materials it has …
Purification processes of xenogeneic bone substitutes and their impact on tissue reactions and regeneration
Xenogeneic bone substitute materials are widely used in oral implantology. Prior to their
clinical use, purification of the former bone tissue has to be conducted to ensure the removal …
clinical use, purification of the former bone tissue has to be conducted to ensure the removal …
Biphasic bone substitutes coated with PLGA incorporating therapeutic ions Sr2+ and Mg2+: cytotoxicity cascade and in vivo response of immune and bone …
The incorporation of bioactive ions into biomaterials has gained significant attention as a
strategy to enhance bone tissue regeneration on the molecular level. However, little …
strategy to enhance bone tissue regeneration on the molecular level. However, little …
In vivo biocompatibility investigation of an injectable calcium carbonate (vaterite) as a bone substitute including compositional analysis via SEM-EDX technology
RE Unger, S Stojanovic, L Besch, S Alkildani… - International Journal of …, 2022 - mdpi.com
Injectable bone substitutes (IBS) are increasingly being used in the fields of orthopedics and
maxillofacial/oral surgery. The rheological properties of IBS allow for proper and less …
maxillofacial/oral surgery. The rheological properties of IBS allow for proper and less …
[PDF][PDF] Platelet-rich fibrin secretome induces three dimensional angiogenic activation in vitro
C Herrera-Vizcaíno, E Dohle, S Al-Maawi, P Booms… - Eur Cell …, 2019 - ecmjournal.org
Different tissue engineering techniques are used to support rapid vascularisation. A novel
technique is the use of platelet-rich fibrin (PRF), an autologous source of growth factors. This …
technique is the use of platelet-rich fibrin (PRF), an autologous source of growth factors. This …
Efficacy of i-PRF in regenerative endodontics therapy for mature permanent teeth with pulp necrosis: study protocol for a multicentre randomised controlled trial
Y Liang, R Ma, L Chen, X Dai, S Zuo, W Jiang, N Hu… - Trials, 2021 - Springer
Background Dental pulp necrosis, a common health problem, is traditionally treated with root
canal therapy; however, it fails in restoring the vitality of damaged pulp. Most studies …
canal therapy; however, it fails in restoring the vitality of damaged pulp. Most studies …