[HTML][HTML] Mechanistic insights into the developmental origin of pediatric hematological disorders

G Camiolo, CG Mullen, K Ottersbach - Experimental Hematology, 2024 - Elsevier
Embryonic and fetal hematopoietic stem and progenitor cells differ in some key properties
from cells that are part of the adult hematopoietic system. These include higher proliferation …

Emerging genetic technologies informing personalized medicine in Shwachman-Diamond syndrome and other inherited BMF disorders

AH Cull, DG Kent, AJ Warren - Blood, 2024 - ashpublications.org
Abstract Ribosomopathy Shwachman-Diamond syndrome (SDS) is a rare autosomal
recessive inherited bone marrow failure syndrome (IBMFS) caused by mutations in the …

Emerging genetic technologies informing personalized medicine in SDS and other inherited bone marrow failure disorders

AH Cull, DG Kent, AJ Warren - Blood Journal, 2024 - ashpublications.org
The ribosomopathy Shwachman-Diamond syndrome (SDS) is a rare autosomal recessive
inherited bone marrow failure syndrome (IBMFS) caused by mutations in the Shwachman …

Clonal hematopoiesis in cancer predisposition syndromes

K Yoshida - International Journal of Hematology, 2024 - Springer
After recent advances in sequencing technologies led to the discovery of novel genes
associated with predisposition to hematological malignancies, studies have now shown that …

Azacitidine combined with venetoclax alleviates AML-MR with TP53 mutation in SDS: a case report and literature review

C Ma, H Lang, Y Chen, L Yang, C Wang, L Han… - Anti-Cancer …, 2024 - journals.lww.com
Shwachman-Diamond syndrome (SDS) is an autosomal recessive genetic disease, which is
prone to transform into myelodysplastic syndrome (MDS) and acute myeloid leukemia …

[PDF][PDF] COLLEGE OF ART AND SCIENCES

HUI SUN - 2023 - repository.lib.fsu.edu
The stochastic control problem is widely applicable in many fields including engineering and
financial mathematics. There exists an extensive literature of work describing both the …

Ribosome abundance, not paralogue composition, is essential for germline development

KZA Grobicki, D Gebert, C Sun, FK Teixeira - bioRxiv, 2024 - biorxiv.org
Ribosomes catalyse all protein synthesis, and mutations altering their levels and function
underlie many developmental diseases and cancer. Historically considered to be invariant …

Structure and Function Studies of Methylation and Pseudouridylation on Ribosome Biogenesis

C Xu - 2024 - repository.lib.fsu.edu
The Eukaryotic cells employ a sophisticated process to generate properly
assembledribosomes. This intricate process commences in the nucleolus through the …