Background The number of studies addressing per-and polyfluoroalkyl substances (PFAS)
and cancer is increasing. Many communities have had water contaminated by PFAS, and …

The methodological advances in epidemiology have facilitated the use of the Danish Civil
Registration System (CRS) in ways not previously described systematically. We reviewed …

Background Concerns have been raised about the possibility that inhibitors of the renin–
angiotensin–aldosterone system (RAAS) could predispose individuals to severe COVID-19; …

Purpose This study examined associations of gender identity and sexual orientation with self-
reported eating disorder (SR-ED) diagnosis and compensatory behaviors in transgender …

Endogenous selection bias is a central problem for causal inference. Recognizing the
problem, however, can be difficult in practice. This article introduces a purely graphical way …

Metabolomic discovery of biomarkers of type 2 diabetes (T2D) risk may reveal etiological
pathways and help to identify individuals at risk for disease. We prospectively investigated …

Objectives: The objective of this study was to systematically review the epidemiological
evidence for an association between periodontitis (PD) and incident atherosclerotic …

Much medical research is observational. The reporting of observational studies is often of
insufficient quality. Poor reporting hampers the assessment of the strengths and …

Summary Background Pre-exposure prophylaxis (PrEP) has shown high efficacy in clinical
trials, but few observational studies have confirmed its effectiveness when prescribed in real …

ContextAdiponectin, a recently discovered adipocyte-derived peptide, is involved in the
regulation of insulin sensitivity and lipid oxidation and, purportedly, in the development of …