Current progress and open challenges for applying deep learning across the biosciences
Deep Learning (DL) has recently enabled unprecedented advances in one of the grand
challenges in computational biology: the half-century-old problem of protein structure …
challenges in computational biology: the half-century-old problem of protein structure …
Deep learning in bioinformatics: Introduction, application, and perspective in the big data era
Deep learning, which is especially formidable in handling big data, has achieved great
success in various fields, including bioinformatics. With the advances of the big data era in …
success in various fields, including bioinformatics. With the advances of the big data era in …
Machine‐Learning‐Assisted Nanozyme Design: Lessons from Materials and Engineered Enzymes
Nanozymes are nanomaterials that exhibit enzyme‐like biomimicry. In combination with
intrinsic characteristics of nanomaterials, nanozymes have broad applicability in materials …
intrinsic characteristics of nanomaterials, nanozymes have broad applicability in materials …
Using deep learning to annotate the protein universe
Understanding the relationship between amino acid sequence and protein function is a long-
standing challenge with far-reaching scientific and translational implications. State-of-the-art …
standing challenge with far-reaching scientific and translational implications. State-of-the-art …
DM3Loc: multi-label mRNA subcellular localization prediction and analysis based on multi-head self-attention mechanism
Subcellular localization of messenger RNAs (mRNAs), as a prevalent mechanism, gives
precise and efficient control for the translation process. There is mounting evidence for the …
precise and efficient control for the translation process. There is mounting evidence for the …
UDSMProt: universal deep sequence models for protein classification
Motivation Inferring the properties of a protein from its amino acid sequence is one of the key
problems in bioinformatics. Most state-of-the-art approaches for protein classification are …
problems in bioinformatics. Most state-of-the-art approaches for protein classification are …
Deep learning with logical constraints
In recent years, there has been an increasing interest in exploiting logically specified
background knowledge in order to obtain neural models (i) with a better performance,(ii) …
background knowledge in order to obtain neural models (i) with a better performance,(ii) …
Coherent hierarchical multi-label classification networks
Hierarchical multi-label classification (HMC) is a challenging classification task extending
standard multi-label classification problems by imposing a hierarchy constraint on the …
standard multi-label classification problems by imposing a hierarchy constraint on the …
Detrac: Transfer learning of class decomposed medical images in convolutional neural networks
Due to the high availability of large-scale annotated image datasets, paramount progress
has been made in deep convolutional neural networks (CNNs) for image classification tasks …
has been made in deep convolutional neural networks (CNNs) for image classification tasks …
Protein–RNA interaction prediction with deep learning: structure matters
Protein–RNA interactions are of vital importance to a variety of cellular activities. Both
experimental and computational techniques have been developed to study the interactions …
experimental and computational techniques have been developed to study the interactions …