Multifunctional biomolecule nanostructures for cancer therapy
J Wang, Y Li, G Nie - Nature Reviews Materials, 2021 - nature.com
Biomolecule-based nanostructures are inherently multifunctional and harbour diverse
biological activities, which can be explored for cancer nanomedicine. The supramolecular …
biological activities, which can be explored for cancer nanomedicine. The supramolecular …
Recent advancements in liposome technology
The liposomes have continued to be well-recognized as an important nano-sized drug
delivery system with attractive properties, such a characteristic bilayer structure assembling …
delivery system with attractive properties, such a characteristic bilayer structure assembling …
Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats
Orthopedic implants containing biodegradable magnesium have been used for fracture
repair with considerable efficacy; however, the underlying mechanisms by which these …
repair with considerable efficacy; however, the underlying mechanisms by which these …
Strategies for non-viral vectors targeting organs beyond the liver
In recent years, nanoparticles have evolved to a clinical modality to deliver diverse nucleic
acids. Rising interest in nanomedicines comes from proven safety and efficacy profiles …
acids. Rising interest in nanomedicines comes from proven safety and efficacy profiles …
[HTML][HTML] Exosome-guided bone targeted delivery of Antagomir-188 as an anabolic therapy for bone loss
Y Hu, X Li, Q Zhang, Z Gu, Y Luo, J Guo, X Wang… - Bioactive materials, 2021 - Elsevier
The differentiation shift from osteogenesis to adipogenesis of bone marrow mesenchymal
stem cells (BMSCs) characterizes many pathological bone loss conditions. Stromal cell …
stem cells (BMSCs) characterizes many pathological bone loss conditions. Stromal cell …
Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formation
Emerging evidence indicates that osteoclasts direct osteoblastic bone formation. MicroRNAs
(miRNAs) have a crucial role in regulating osteoclast and osteoblast function. However …
(miRNAs) have a crucial role in regulating osteoclast and osteoblast function. However …
Development of biodegradable Zn-1X binary alloys with nutrient alloying elements Mg, Ca and Sr
Biodegradable metals have attracted considerable attentions in recent years. Besides the
early launched biodegradable Mg and Fe metals, Zn, an essential element with osteogenic …
early launched biodegradable Mg and Fe metals, Zn, an essential element with osteogenic …
[HTML][HTML] Bone-targeted bioengineered bacterial extracellular vesicles delivering siRNA to ameliorate osteoporosis
H Liu, H Zhang, S Wang, J Cui, W Weng, X Liu… - Composites Part B …, 2023 - Elsevier
Osteoporosis (OP), characterized by decreased bone mass and destruction of bone
microarchitecture, is the most common bone degenerative disease. Conventional treatments …
microarchitecture, is the most common bone degenerative disease. Conventional treatments …
The development of functional non-viral vectors for gene delivery
S Patil, YG Gao, X Lin, Y Li, K Dang, Y Tian… - International journal of …, 2019 - mdpi.com
Gene therapy is manipulation in/of gene expression in specific cells/tissue to treat diseases.
This manipulation is carried out by introducing exogenous nucleic acids, such as DNA or …
This manipulation is carried out by introducing exogenous nucleic acids, such as DNA or …
Adjuvant physiochemistry and advanced nanotechnology for vaccine development
Vaccines comprising innovative adjuvants are rapidly reaching advanced translational
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …