Efficient drug delivery systems (DDSs) play a pivotal role in ensuring pharmaceuticals'
targeted and effective administration. However, the intricate interplay between drug …

Personalised drug delivery enables a tailored treatment plan for each patient compared to
conventional drug delivery, where a generic strategy is commonly employed. It can not only …

To understand how the microvasculature grows and remodels, researchers require
reproducible systems that emulate the function of living tissue. Innovative contributions …

Structural changes to microvascular networks are increasingly highlighted as markers of
pathogenesis in a wide range of disease, eg Alzheimer's disease, vascular dementia and …

Drug delivery to solid tumour involves multiple physiological, biochemical and biophysical
processes taking place across a wide range of length and time scales. The therapeutic …

Nanoparticles tethered with vasculature-binding epitopes have been used to deliver the
drug into injured or diseased tissues via the bloodstream. However, the extent that blood …

Geothermal district heating development has been gaining momentum in Europe with
numerous deep geothermal installations and projects currently under development. With the …

Multiscale methods based on coupled partial differential equations defined on bulk and
embedded manifolds are still poorly explored from the theoretical standpoint, although they …

Nanomedicine aims to increase the effectiveness of therapeutic and diagnostic agents by
exploiting unique properties that arise when operating at the nanoscale. Despite the recent …

We address a mathematical model for oxygen transfer in the microcirculation. The model
includes blood flow and hematocrit transport coupled with the interstitial flow, oxygen …