Cellular senescence entails a permanent proliferative arrest, coupled to multiple phenotypic
changes. Among these changes is the release of numerous biologically active molecules …

Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …

Senescent endothelial cells (ECs) could impair the integrity of the blood vessel endothelium,
leading to vascular aging and a series of diseases, such as atherosclerosis, diabetes …

Ketone bodies play significant roles in organismal energy homeostasis, serving as oxidative
fuels, modulators of redox potential, lipogenic precursors, and signals, primarily during …

Prospective molecular targets and therapeutic applications for ketone body metabolism
have increased exponentially in the past decade. Initially considered to be restricted in …

Background: Open Access Editor's Choice Review The Ketogenic Diet and Cardiovascular
Diseases by Damian Dyńka, Katarzyna Kowalcze, Anna Charuta and Agnieszka …

Despite major efforts to reduce atherosclerotic cardiovascular disease (ASCVD) burden with
conventional risk factor control, significant residual risk remains. Recent evidence on non …

Cardiovascular diseases (CVDs) constitute the prime cause of global mortality, with an
immense impact on patient quality of life and disability. Clinical evidence has revealed a …

The epidemic of obesity is a major challenge for health policymakers due to its far-reaching
effects on population health and potentially overwhelming financial burden on healthcare …

Senescent cells are generally characterized by permanent cell cycle arrest, metabolic
alteration and activation, and apoptotic resistance in multiple organs due to various …