The neural basis of psychedelic action

AC Kwan, DE Olson, KH Preller, BL Roth - Nature Neuroscience, 2022 - nature.com
Psychedelics are serotonin 2A receptor agonists that can lead to profound changes in
perception, cognition and mood. In this review, we focus on the basic neurobiology …

[HTML][HTML] Pharmacological, neural, and psychological mechanisms underlying psychedelics: A critical review

M van Elk, DB Yaden - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
This paper provides a critical review of several possible mechanisms at different levels of
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …

Default mode network modulation by psychedelics: a systematic review

JJ Gattuso, D Perkins, S Ruffell… - International Journal …, 2023 - academic.oup.com
Psychedelics are a unique class of drug that commonly produce vivid hallucinations as well
as profound psychological and mystical experiences. A grou** of interconnected brain …

A complex systems perspective on psychedelic brain action

M Girn, FE Rosas, RE Daws, CL Gallen… - Trends in Cognitive …, 2023 - cell.com
Recent findings suggesting the potential transdiagnostic efficacy of psychedelic-assisted
therapy have fostered the need to deepen our understanding of psychedelic brain action …

Mechanisms and molecular targets surrounding the potential therapeutic effects of psychedelics

AM Jaster, J González-Maeso - Molecular psychiatry, 2023 - nature.com
Psychedelics, also known as classical hallucinogens, have been investigated for decades
due to their potential therapeutic effects in the treatment of neuropsychiatric and substance …

Psychedelics and neural plasticity: therapeutic implications

SF Grieco, E Castrén, GM Knudsen… - Journal of …, 2022 - Soc Neuroscience
Psychedelic drugs have reemerged as tools to treat several brain disorders. Cultural
attitudes toward them are changing, and scientists are once again investigating the neural …

Clinically relevant acute subjective effects of psychedelics beyond mystical experience

DB Yaden, SP Goldy, B Weiss… - Nature Reviews …, 2024 - nature.com
The administration of classic psychedelics has been associated with well-being and mental
health benefits as well as risks and adverse events. The acute subjective effects of …

[HTML][HTML] Psychedelic resting-state neuroimaging: A review and perspective on balancing replication and novel analyses

E Drummond, W McCulloch, GM Knudsen… - Neuroscience & …, 2022 - Elsevier
Clinical research into serotonergic psychedelics is expanding rapidly, showing promising
efficacy across myriad disorders. Resting-state functional magnetic resonance imaging (rs …

Comparison of psychedelic and near-death or other non-ordinary experiences in changing attitudes about death and dying

MM Sweeney, S Nayak, ES Hurwitz, LN Mitchell… - Plos one, 2022 - journals.plos.org
Both psychedelic drug experiences and near-death experiences can occasion changes in
perspectives on death and dying, but there have been few direct comparisons of these …

[HTML][HTML] More than meets the eye: The role of sensory dimensions in psychedelic brain dynamics, experience, and therapeutics

M Aqil, L Roseman - Neuropharmacology, 2023 - Elsevier
Psychedelics are undergoing a major resurgence of scientific and clinical interest. While
multiple theories and frameworks have been proposed, there is yet no universal agreement …