Neurotransmitter modulation by the gut microbiota

P Strandwitz - Brain research, 2018 - Elsevier
The gut microbiota–the trillions of bacteria that reside within the gastrointestinal tract–has
been found to not only be an essential component immune and metabolic health, but also …

Serotonin, tryptophan metabolism and the brain-gut-microbiome axis

SM O'Mahony, G Clarke, YE Borre, TG Dinan… - Behavioural brain …, 2015 - Elsevier
The brain-gut axis is a bidirectional communication system between the central nervous
system and the gastrointestinal tract. Serotonin functions as a key neurotransmitter at both …

Minireview: gut microbiota: the neglected endocrine organ

G Clarke, RM Stilling, PJ Kennedy… - Molecular …, 2014 - academic.oup.com
The concept that the gut microbiota serves as a virtual endocrine organ arises from a
number of important observations. Evidence for a direct role arises from its metabolic …

Gut microbes and metabolites as modulators of blood-brain barrier integrity and brain health

A Parker, S Fonseca, SR Carding - Gut microbes, 2020 - Taylor & Francis
The human gastrointestinal (gut) microbiota comprises diverse and dynamic populations of
bacteria, archaea, viruses, fungi, and protozoa, coexisting in a mutualistic relationship with …

Probiotics, prebiotics and postbiotics on mitigation of depression symptoms: modulation of the brain–gut–microbiome axis

A Chudzik, A Orzyłowska, R Rola, GJ Stanisz - Biomolecules, 2021 - mdpi.com
The brain–gut–microbiome axis is a bidirectional communication pathway between the gut
microbiota and the central nervous system. The growing interest in the gut microbiota and …

Relationship between the gut microbiome and brain function

MH Mohajeri, G La Fata, RE Steinert… - Nutrition …, 2018 - academic.oup.com
It has become increasingly evident in recent years that the gut microbiome and the brain
communicate in a bidirectional manner, with each possibly affecting the other's functions …

Associations of neurotransmitters and the gut microbiome with emotional distress in mixed type of irritable bowel syndrome

ZA Barandouzi, J Lee, M del Carmen Rosas, J Chen… - Scientific Reports, 2022 - nature.com
Evidence highlights the comorbidity between emotional distress and irritable bowel
syndrome (IBS) through the gut-brain axis. However, the underlying mechanism is largely …

[HTML][HTML] A forward chemical genetic screen reveals gut microbiota metabolites that modulate host physiology

H Chen, PK Nwe, Y Yang, CE Rosen, AA Bielecka… - Cell, 2019 - cell.com
The intestinal microbiota produces tens of thousands of metabolites. Here, we used host
sensing of small molecules by G-protein coupled receptors (GPCRs) as a lens to illuminate …

Tryptophan metabolites along the microbiota-gut-brain axis: an interkingdom communication system influencing the gut in health and disease

A Bosi, D Banfi, M Bistoletti… - International Journal of …, 2020 - journals.sagepub.com
The 'microbiota-gut-brain axis' plays a fundamental role in maintaining host homeostasis,
and different immune, hormonal, and neuronal signals participate to this interkingdom …

Where is dopamine and how do immune cells see it?: dopamine-mediated immune cell function in health and disease

SM Matt, PJ Gaskill - Journal of Neuroimmune Pharmacology, 2020 - Springer
Dopamine is well recognized as a neurotransmitter in the brain, and regulates critical
functions in a variety of peripheral systems. Growing research has also shown that …