Fields studying movement generation, including robotics, psychology, cognitive science,
and neuroscience utilize concepts and tools related to the pervasiveness of variability in …

Until recently, quantitative studies of walking have typically focused on properties of a typical
or average stride, ignoring the stride-to-stride fluctuations and considering these fluctuations …

Friedreichʼs ataxia (FA) is caused by a variant of the Frataxin (FXN) gene, leading to its
downregulation and progressively impaired cardiac and neurological function. Current gold …

The healthy heartbeat is traditionally thought to be regulated according to the classical
principle of homeostasis whereby physiologic systems operate to reduce variability and …

According to classical concepts of physiologic control, healthy systems are self-regulated to
reduce variability and maintain physiologic constancy. Contrary to the predictions of …

A defining but elusive feature of physiologic systems is their daunting complexity. This
complexity arises from the interaction of a myriad of structural units and regulatory feedback …

Hausdorff, Jeffrey M., Susan L. Mitchell, Renée Firtion, CK Peng, Merit E. Cudkowicz,
Jeanne Y. Wei, and Ary L. Goldberger. Altered fractal dynamics of gait: reduced stride …

The study of gait variability, the stride-to-stride fluctuations in walking, offers a
complementary way of quantifying locomotion and its changes with aging and disease as …

Falling poses a major threat to the steadily growing population of the elderly in modern-day
society. A major challenge in the prevention of falls is the identification of individuals who …

Parkinson's disease (PD) is a common, debilitating neurodegenerative disease. Gait
disturbances are a frequent cause of disability and impairment for patients with PD. This …