Several mechanisms have been proposed for histone marks to exert their functions,
including altering the physical properties of nucleosomes by neutralization of charge via …

Mass spectrometry (MS) is the most comprehensive and versatile tool in large-scale
proteomics. In this review, we dissect the overall framework of the MS experiment into its key …

Brown adipose tissue (BAT) is best known for thermogenesis. Rodent studies demonstrated
that enhanced BAT thermogenesis is tightly associated with increased energy expenditure …

Mass spectrometry has transformed the field of cell signaling by enabling global studies of
dynamic protein phosphorylation ('phosphoproteomics'). Recent developments are enabling …

Plant cells are immobile; thus, plant growth and development depend on cell expansion
rather than cell migration. The molecular mechanism by which the plasma membrane …

The target of rapamycin (TOR) kinase is a conserved regulatory hub that translates
environmental and nutritional information into permissive or restrictive growth decisions …

Plasma membrane H+-ATPase provides the driving force for light-induced stomatal opening.
However, the mechanisms underlying the regulation of its activity remain unclear. Here, we …

Abscisic acid (ABA) signaling is important for stress responses and developmental
processes in plants. A subgroup of protein phosphatase 2C (group A PP2C) or SNF1-related …

Abscisic acid (ABA) is a phytohormone that regulates diverse plant processes, including
seed germination and the response to dehydration. In Arabidopsis thaliana, protein kinases …

Mass spectrometry (MS)-based proteomics has become the preferred tool for the analysis of
protein phosphorylation. To be successful at such an endeavor, there is a requirement for an …