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[HTML][HTML] Models of osteoarthritis: the good, the bad and the promising
Osteoarthritis (OA) is a chronic degenerative disease of diarthrodial joints most commonly
affecting people over the age of forty. The causes of OA are still unknown and there is much …
affecting people over the age of forty. The causes of OA are still unknown and there is much …
Sequencing technologies and genome sequencing
The high-throughput-next generation sequencing (HT-NGS) technologies are currently the
hottest topic in the field of human and animals genomics researches, which can produce …
hottest topic in the field of human and animals genomics researches, which can produce …
De novo assembly of the cattle reference genome with single-molecule sequencing
Background Major advances in selection progress for cattle have been made following the
introduction of genomic tools over the past 10–12 years. These tools depend upon the Bos …
introduction of genomic tools over the past 10–12 years. These tools depend upon the Bos …
De novo assembly of haplotype-resolved genomes with trio binning
Complex allelic variation hampers the assembly of haplotype-resolved sequences from
diploid genomes. We developed trio binning, an approach that simplifies haplotype …
diploid genomes. We developed trio binning, an approach that simplifies haplotype …
Large-scale ruminant genome sequencing provides insights into their evolution and distinct traits
INTRODUCTION The ruminants are one of the most successful mammalian lineages,
exhibiting extensive morphological and ecological diversity and containing several key …
exhibiting extensive morphological and ecological diversity and containing several key …
Building a livestock genetic and genomic information knowledgebase through integrative developments of Animal QTLdb and CorrDB
Successful development of biological databases requires accommodation of the burgeoning
amounts of data from high-throughput genomics pipelines. As the volume of curated data in …
amounts of data from high-throughput genomics pipelines. As the volume of curated data in …
Meta-analysis of genome-wide association studies for cattle stature identifies common genes that regulate body size in mammals
Stature is affected by many polymorphisms of small effect in humans. In contrast, variation in
dogs, even within breeds, has been suggested to be largely due to variants in a small …
dogs, even within breeds, has been suggested to be largely due to variants in a small …
Whole-genome sequencing of 234 bulls facilitates map** of monogenic and complex traits in cattle
The 1000 bull genomes project supports the goal of accelerating the rates of genetic gain in
domestic cattle while at the same time considering animal health and welfare by providing …
domestic cattle while at the same time considering animal health and welfare by providing …
Single-molecule sequencing and chromatin conformation capture enable de novo reference assembly of the domestic goat genome
The decrease in sequencing cost and increased sophistication of assembly algorithms for
short-read platforms has resulted in a sharp increase in the number of species with genome …
short-read platforms has resulted in a sharp increase in the number of species with genome …
Comparative genomics reveals insights into avian genome evolution and adaptation
Birds are the most species-rich class of tetrapod vertebrates and have wide relevance
across many research fields. We explored bird macroevolution using full genomes from 48 …
across many research fields. We explored bird macroevolution using full genomes from 48 …