Biomaterials have played an increasingly prominent role in the success of biomedical
devices and in the development of tissue engineering, which seeks to unlock the …

Due to the lack of success in small-diameter (< 6 mm) prosthetic vascular grafts, a variety of
strategies have evolved utilizing a tissue-engineering approach. Much of this work has …

For years intensive research has been done to improve the hemocompatibility of blood
contacting vascular devices. Despite the enormous progress in physicochemical surface …

Cell therapy for the treatment of cardiovascular disease has been hindered by low cell
engraftment, poor survival, and inadequate phenotype and function. In this study, we added …

Cardiovascular disease is a primary cause of mortality worldwide, and patients often require
bypass surgery that utilizes autologous vessels as conduits. However, the limited availability …

expanded from cardiac biopsies by different protocols. 9, 10 Very recently, the first patients
were treated with either cardiosphere-derived cardiac stem cells (CArdiosphere-Derived …

Appropriate mechanical properties and fast endothelialization of synthetic grafts are key to
ensure long-term functionality of implants. We used a newly developed biostable …

Biology and Engineering of Stem Cell Niches covers a wide spectrum of research and
current knowledge on embryonic and adult stem cell niches, focusing on the understanding …

Myopathies of skeletal muscle are prevalent diseases worldwide. To address this,
regenerative therapies are being developed to restore perfusion to ischemic muscle and to …

Although many regenerative cell therapies are being developed to replace or regenerate
ischaemic muscle, the lack of vasculature and poor persistence of the therapeutic cells …