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The history of enterovirus A71 outbreaks and molecular epidemiology in the Asia-Pacific region
Abstract Enterovirus A71 (EV-A71) is one of the common causative pathogens for hand foot
and mouth disease (HFMD) affecting young children. HFMD outbreak can result in a …
and mouth disease (HFMD) affecting young children. HFMD outbreak can result in a …
World-wide prevalence and genotype distribution of enteroviruses
L Brouwer, G Moreni, KC Wolthers, D Pajkrt - Viruses, 2021 - mdpi.com
Enteroviruses (EVs) are highly prevalent viruses world-wide, causing a wide range of
diseases in both children and adults. Insight in the global prevalence of EVs is important to …
diseases in both children and adults. Insight in the global prevalence of EVs is important to …
Enterovirus-associated hand-foot and mouth disease and neurological complications in Japan and the rest of the world
Enteroviruses (EVs) are responsible for extremely large-scale, periodic epidemics in
pediatric cohorts, particularly in East and Southeast Asia. Clinical presentation includes a …
pediatric cohorts, particularly in East and Southeast Asia. Clinical presentation includes a …
IRES-targeting small molecule inhibits enterovirus 71 replication via allosteric stabilization of a ternary complex
J Davila-Calderon, NN Patwardhan, LY Chiu… - Nature …, 2020 - nature.com
Abstract Enterovirus 71 (EV71) poses serious threats to human health, particularly in
Southeast Asia, and no drugs or vaccines are available. Previous work identified the stem …
Southeast Asia, and no drugs or vaccines are available. Previous work identified the stem …
RNA–small-molecule interaction: challenging the “undruggable” tag
RNA targeting, specifically with small molecules, is a relatively new and rapidly emerging
avenue with the promise to expand the target space in the drug discovery field. From being …
avenue with the promise to expand the target space in the drug discovery field. From being …
Insight into the Enterovirus A71: A review
Enterovirus A71 is a major causative pathogen of hand, foot and mouth disease. It has
become a global public health threat, and is especially important for infants and young …
become a global public health threat, and is especially important for infants and young …
Epidemiology and sequence-based evolutionary analysis of circulating non-polio enteroviruses
Enteroviruses (EVs) are positive-sense RNA viruses, with over 50,000 nucleotide
sequences publicly available. While most human infections are typically associated with …
sequences publicly available. While most human infections are typically associated with …
Clinical, etiological and epidemiological investigations of hand, foot and mouth disease in southern Vietnam during 2015–2018
Hand, foot and mouth disease (HFMD) continues to challenge Asia with pandemic potential.
In Vietnam, there have been two major outbreaks occurring during 2011–2012 (> 200,000 …
In Vietnam, there have been two major outbreaks occurring during 2011–2012 (> 200,000 …
Epidemic curves made easy using the R package incidence
ZN Kamvar, J Cai, JRC Pulliam… - …, 2019 - pmc.ncbi.nlm.nih.gov
The epidemiological curve (epicurve) is one of the simplest yet most useful tools used by
field epidemiologists, modellers, and decision makers for assessing the dynamics of …
field epidemiologists, modellers, and decision makers for assessing the dynamics of …
Berberine prevents lethal EV71 neurological infection in newborn mice
G Cui, H Wang, C Yang, X Zhou, J Wang… - Frontiers in …, 2022 - frontiersin.org
Enterovirus 71 (EV71) is the major pathogen causing fatal neurological complications of
hand, foot, and mouth disease (HFMD) in young children. Currently no effective antiviral …
hand, foot, and mouth disease (HFMD) in young children. Currently no effective antiviral …