Recognition in the domain of molecular chirality: from noncovalent interactions to separation of enantiomers

P Peluso, B Chankvetadze - Chemical Reviews, 2022 - ACS Publications
It is not a coincidence that both chirality and noncovalent interactions are ubiquitous in
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …

Chiral recognition in separation science–an update

GKE Scriba - Journal of Chromatography a, 2016 - Elsevier
Stereospecific recognition of chiral molecules is an important issue in various aspects of life
sciences and chemistry including analytical separation sciences. The basis of analytical …

Noncovalent interactions in high-performance liquid chromatography enantioseparations on polysaccharide-based chiral selectors

P Peluso, V Mamane, R Dallocchio, A Dessì… - … of Chromatography A, 2020 - Elsevier
Designed more than thirty years ago in order to improve and maximize the discrimination
capability of native polysaccharides, cellulose-and amylose-based selectors have shown …

Engineering an alcohol dehydrogenase with enhanced activity and stereoselectivity toward diaryl ketones: reduction of steric hindrance and change of the …

K Wu, Z Yang, X Meng, R Chen, J Huang… - Catalysis Science & …, 2020 - pubs.rsc.org
Steric hindrance in the binding pocket of an alcohol dehydrogenase (ADH) has a great
impact on its activity and stereoselectivity simultaneously. Due to the subtle structural …

Stereoselective processes based on σ-hole interactions

P Peluso, V Mamane - Molecules, 2022 - mdpi.com
The σ-hole interaction represents a noncovalent interaction between atoms with σ-hole (s)
on their surface (such as halogens and chalcogens) and negative sites. Over the last …

Homochiral metal–organic frameworks and their application in chromatography enantioseparations

P Peluso, V Mamane, S Cossu - Journal of Chromatography A, 2014 - Elsevier
The last frontier in the chiral stationary phases (CSPs) field for chromatography
enantioseparations is represented by homochiral metal-organic frameworks (MOFs), a class …

Disubstituted ferrocenyl iodo-and chalcogenoalkynes as chiral halogen and chalcogen bond donors

V Mamane, P Peluso, E Aubert, R Weiss… - …, 2020 - ACS Publications
Asymmetric catalysis based on halogen and chalcogen bonds (XB and ChB) is in its infancy,
and the search for new chiral XB and ChB donors represents a crucial step toward its …

[HTML][HTML] Unravelling dispersion forces in liquid-phase enantioseparation. Part I: Impact of ferrocenyl versus phenyl groups

B Sechi, A Dessì, R Dallocchio, N Tsetskhladze… - Analytica Chimica …, 2023 - Elsevier
Background Highly ordered chiral secondary structures as well as multiple (tunable)
recognition sites are the keys to success of polysaccharide carbamate-based chiral …

Halogen bond in separation science: A critical analysis across experimental and theoretical results

P Peluso, V Mamane, A Dessì, R Dallocchio… - … of Chromatography A, 2020 - Elsevier
The halogen bond (XB) is a noncovalent interaction involving a halogen acting as
electrophile and a Lewis base. In the last decades XB has found practical application in …

Recent studies of docking and molecular dynamics simulation for liquid‐phase enantioseparations

P Peluso, A Dessì, R Dallocchio, V Mamane… - …, 2019 - Wiley Online Library
Liquid‐phase enantioseparations have been fruitfully applied in several fields of science.
Various applications along with technical and theoretical advancements contributed to …