Fluorescent probes are one of the cornerstones of real-time imaging of live cells and a
powerful tool for cell biologists. They provide high sensitivity and great versatility while …

Dynamic molecular interactions are fundamental to all cellular processes. In vivo analyses of
these interactions are frequently done using fluorescence recovery after photobleaching …

Fluorescence recovery after photobleaching (FRAP) is now widely used to investigate
binding interactions in live cells. Although various idealized solutions have been identified …

Focal adhesions (FAs) are mechanosensitive adhesion and signaling complexes that grow
and change composition in response to myosin II–mediated cytoskeletal tension in a …

Cells exhibit a biphasic migration-velocity response to increasing adhesion strength, with
fast migration occurring at intermediate extracellular matrix (ECM) concentration and slow …

Within cells, motor and non-motor microtubule-associated proteins (MAPs) simultaneously
converge on the microtubule. How the binding activities of non-motor MAPs are coordinated …

Classical microtubule‐associated proteins (MAPs) were originally identified based on their
co‐purification with microtubules assembled from mammalian brain lysate. They have since …

Background: To test current models for how unattached and untense kinetochores prevent
Cdc20 activation of the anaphase-promoting complex/cyclosome (APC/C) throughout the …

Fluorescent tools have emerged as an important tool for studying the distinct chemical
microenvironments of organelles, due to their high specificity and ability to be used in non …

Genetic or pharmacological alteration of the activity of the histone deacetylase 6 (HDAC6)
induces a parallel alteration in cell migration. Using tubacin to block deacetylation of α …