Primary nonfunction and early allograft dysfunction after liver transplantation

Ł Masior, M Grąt - Digestive Diseases, 2022 - karger.com
Background: Despite continuous progress in the field of liver transplantation, considerable
proportion of patients still suffer from the postoperative graft dysfunction. Clinically, it …

SIRT3 a Major Player in Attenuation of Hepatic Ischemia‐Reperfusion Injury by Reducing ROS via Its Downstream Mediators: SOD2, CYP‐D, and HIF‐1α

G Katwal, D Baral, X Fan, H Weiyang… - Oxidative medicine …, 2018 - Wiley Online Library
Reactive oxygen species (ROS) production in hepatic ischemia‐reperfusion injury (IRI) is a
complex process where multiple cellular and molecular pathways are involved. Few of those …

Remote ischemic conditioning: a promising therapeutic intervention for multi-organ protection

D Zhou, J Ding, J Ya, L Pan, Y Wang, X Ji… - Aging (Albany …, 2018 - pmc.ncbi.nlm.nih.gov
Despite decades of formidable exploration, multi-organ ischemia-reperfusion injury (IRI)
encountered, particularly amongst elderly patients with clinical scenarios, such as age …

Liver ischemia and reperfusion injury. Pathophysiology and new horizons in preconditioning and therapy

PCG Nakazato, JP Victorino, CF Fina… - Acta cirurgica …, 2018 - SciELO Brasil
It is well known that during hepatic operative procedures, it is often critical that the irrigation
is interrupted to avoid possible bleeding, blood transfusions, variable intensities, and their …

Hemorheological and microcirculatory factors in liver ischemia-reperfusion injury—An update on pathophysiology, molecular mechanisms and protective strategies

N Nemeth, K Peto, Z Magyar, Z Klarik, G Varga… - International Journal of …, 2021 - mdpi.com
Hepatic ischemia-reperfusion injury (IRI) is a multifactorial phenomenon which has been
associated with adverse clinical outcomes. IRI related tissue damage is characterized by …

Effect of remote ischemic preconditioning conducted in living liver donors on postoperative liver function in donors and recipients following liver transplantation: a …

KW Jung, J Kang, HM Kwon, YJ Moon, IG Jun, JG Song… - 2020 - journals.lww.com
Objective: This study aimed to assess the effects of remote ischemic preconditioning (RIPC)
on liver function in donors and recipients after living donor liver transplantation (LDLT) …

An evaluation of ischaemic preconditioning as a method of reducing ischaemia reperfusion injury in liver surgery and transplantation

FP Robertson, BJ Fuller, BR Davidson - Journal of clinical medicine, 2017 - mdpi.com
Liver Ischaemia Reperfusion (IR) injury is a major cause of post-operative liver dysfunction,
morbidity and mortality following liver resection surgery and transplantation. There are no …

[HTML][HTML] Methods of attenuating ischemia-reperfusion injury in liver transplantation for hepatocellular carcinoma

Ł Masior, M Grąt - International journal of molecular sciences, 2021 - mdpi.com
Hepatocellular carcinoma (HCC) is one of the most frequent indications for liver
transplantation. However, the transplantation is ultimately associated with the occurrence of …

Mitochondrial dysfunction and oxidative stress in liver transplantation and underlying diseases: new insights and therapeutics

S Shi, L Wang, LJW van der Laan, Q Pan… - …, 2021 - journals.lww.com
Mitochondria are essential organelles for cellular energy and metabolism. Like with any
organ, the liver highly depends on the function of these cellular powerhouses. Hepatotoxic …

[HTML][HTML] Systematic review on the treatment of deceased organ donors

AC van Erp, LFA van Dullemen, RJ Ploeg… - Transplantation …, 2018 - Elsevier
Background Currently, there is no consensus on which treatments should be a part of
standard deceased-donor management to improve graft quality and transplantation …