Despite advances in neurosurgery, chemotherapy and radiotherapy, glioblastoma remains
one of the most treatment-resistant CNS malignancies, and the tumour inevitably recurs. The …

Glioblastoma multiforme (GBM) is one of the most malignant types of central nervous system
tumors. Despite advances in treatment modalities it remains largely incurable. The objective …

The cytoskeleton of animal cells is one of the most complicated and functionally versatile
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …

Heterotypic interactions across diverse cell types can enable tumor progression and hold
the potential to expand therapeutic interventions. Here, combined profiling and functional …

Patients with glioblastoma (GBM) have a universally poor prognosis and are in urgent need
of effective treatment strategies. Recent advances in sequencing techniques unraveled the …

Abstract Organ‐on‐a‐chip (OOC) platforms recapitulate human in vivo‐like conditions more
realistically compared to many animal models and conventional two‐dimensional cell …

Microglia are the resident brain macrophages and they have been traditionally studied as
orchestrators of the brain inflammatory response during infections and disease. In addition …

Glioma is the prime cause of cancer allied mortality in adolescent people and it accounts
about 80% of all malignant tumours. Eugenol is a major bioactive constituent present in the …

The concept of tumor stem cells (TSCs) provides a new paradigm for understanding tumor
biology, although it remains unclear whether TSCs will prove to be a more robust model …

Before replicating DNA during their reproductive cycle, our cells enter a phase called G1
during which they interpret a flood of signals that influence cell division and cell fate …