“Radiomics” refers to the extraction and analysis of large amounts of advanced quantitative
imaging features with high throughput from medical images obtained with computed …

Solid cancers are spatially and temporally heterogeneous. This limits the use of invasive
biopsy based molecular assays but gives huge potential for medical imaging, which has the …

Tumors exhibit genomic and phenotypic heterogeneity, which has prognostic significance
and may influence response to therapy. Imaging can quantify the spatial variation in …

The increasing use of biomarkers in cancer have led to the concept of personalized
medicine for patients. Personalized medicine provides better diagnosis and treatment …

Purpose: Radiomics, which is the high‐throughput extraction and analysis of quantitative
image features, has been shown to have considerable potential to quantify the tumor …

Dynamic contrast‐enhanced MRI (DCE‐MRI) is a functional MRI method where T1‐
weighted MR images are acquired dynamically after bolus injection of a contrast agent. The …

Computer-aided diagnosis (CAD) has been a popular area of research and development in
the past few decades. In CAD, machine learning methods and multidisciplinary knowledge …

Although cancer often is referred to as “a disease of the genes,” it is indisputable that the
(epi) genetic properties of individual cancer cells are highly variable, even within the same …

Contrast-enhanced magnetic resonance imaging (MRI) is an indispensable tool for
diagnostic medicine. However, safety concerns related to gadolinium in commercial MRI …

About 100 early-phase clinical trials and investigator-led studies of targeted antivascular
therapies—both anti-angiogenic and vascular-targeting agents—have reported data derived …