Design and application of receptor-targeted fluorescent probes based on small molecular fluorescent dyes
Y Zhang, S Li, H Zhang, H Xu - Bioconjugate chemistry, 2021 - ACS Publications
In recent years, a variety of receptor-targeted fluorescent probes have been developed and
widely used to realize the visualization of certain receptors, which facilitates the early …
widely used to realize the visualization of certain receptors, which facilitates the early …
N-Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as Fluorescent Probes to Detect Microglia Activation through the Imaging of …
F Intranuovo, M Majellaro… - Journal of Medicinal …, 2024 - ACS Publications
Cannabinoid receptor subtype 2 (CB2R) is emerging as a pivotal biomarker to identify the
first steps of inflammation-based diseases such as cancer and neurodegeneration. There is …
first steps of inflammation-based diseases such as cancer and neurodegeneration. There is …
[CITATION][C] Goods and bads of the endocannabinoid system as a therapeutic target: Lessons learned after 30 years
Cannabinoids in the cardiovascular system
WSV Ho, MEM Kelly - Advances in Pharmacology, 2017 - Elsevier
Cannabinoids are known to modulate cardiovascular functions including heart rate, vascular
tone, and blood pressure in humans and animal models. Essential components of the …
tone, and blood pressure in humans and animal models. Essential components of the …
Design and synthesis of fluorescent ligands for the detection of cannabinoid type 2 receptor (CB2R)
F Spinelli, R Giampietro, A Stefanachi, C Riganti… - European Journal of …, 2020 - Elsevier
Abstract The Cannabinoid 2 receptor, CB2R, belonging to the endocannabinoid system,
ECS, is involved in the first steps of neurodegeneration and cancer evolution and …
ECS, is involved in the first steps of neurodegeneration and cancer evolution and …
Chemical tools for studying lipid-binding class AG protein–coupled receptors
Cannabinoid, free fatty acid, lysophosphatidic acid, sphingosine 1-phosphate, prostanoid,
leukotriene, bile acid, and platelet-activating factor receptor families are class AG protein …
leukotriene, bile acid, and platelet-activating factor receptor families are class AG protein …
Functionalized cannabinoid subtype 2 receptor ligands: fluorescent, PET, photochromic and covalent molecular probes
F Basagni, M Rosini, M Decker - ChemMedChem, 2020 - Wiley Online Library
Cannabinoid subtype 2 receptors (CB2Rs) are G protein‐coupled receptors (GPCRs)
belonging to the endocannabinoid system, a complex network of signalling pathways …
belonging to the endocannabinoid system, a complex network of signalling pathways …
Translocator protein and new targets for neuroinflammation
M Herrera-Rivero, MT Heneka… - Clinical and Translational …, 2015 - Springer
The mitochondrial translocator protein (18 kDa; TSPO) is involved in a wide array of
physiological processes importantly including cholesterol transport, steroidogenesis and …
physiological processes importantly including cholesterol transport, steroidogenesis and …
Alkyl indole-based cannabinoid type 2 receptor tools: Exploration of linker and fluorophore attachment
Abstract Cannabinoid type 2 (CB 2) receptor continues to emerge as a promising drug target
for many diseases and conditions. New tools for studying CB 2 receptor are required to …
for many diseases and conditions. New tools for studying CB 2 receptor are required to …
In Vivo Dynamic Nuclear Polarization Magnetic Resonance Imaging for the Evaluation of Redox-Related Diseases and Theranostics
F Hyodo, H Eto, T Naganuma, N Koyasu… - Antioxidants & Redox …, 2022 - liebertpub.com
Significance: In vivo molecular and metabolic imaging is an emerging field in biomedical
research that aims to perform noninvasive detection of tissue metabolism in disease states …
research that aims to perform noninvasive detection of tissue metabolism in disease states …