Technological advancements in cancer diagnostics: Improvements and limitations

A Pulumati, A Pulumati, BS Dwarakanath… - Cancer …, 2023 - Wiley Online Library
Background Cancer is characterized by the rampant proliferation, growth, and infiltration of
malignantly transformed cancer cells past their normal boundaries into adjacent tissues. It is …

[HTML][HTML] Upconversion nanoparticles: design, nanochemistry, and applications in theranostics

G Chen, H Qiu, PN Prasad, X Chen - Chemical reviews, 2014 - ACS Publications
Upconversion Nanoparticles: Design, Nanochemistry, and Applications in Theranostics |
Chemical Reviews Recently Viewedclose modal ACS ACS Publications C&EN CAS Find …

SABER amplifies FISH: enhanced multiplexed imaging of RNA and DNA in cells and tissues

JY Kishi, SW Lapan, BJ Beliveau, ER West, A Zhu… - Nature …, 2019 - nature.com
Fluorescence in situ hybridization (FISH) reveals the abundance and positioning of nucleic
acid sequences in fixed samples. Despite recent advances in multiplexed amplification of …

Upconversion-based photodynamic cancer therapy

Y Liu, X Meng, W Bu - Coordination chemistry reviews, 2019 - Elsevier
Photodynamic therapy (PDT) has become widely accepted and utilized for tumor therapy.
Considering the natural shortcomings (eg, lack of an ideal photosensitizer and limited light …

Review of spectral imaging technology in biomedical engineering: achievements and challenges

Q Li, X He, Y Wang, H Liu, D Xu… - Journal of biomedical …, 2013 - spiedigitallibrary.org
Spectral imaging is a technology that integrates conventional imaging and spectroscopy to
get both spatial and spectral information from an object. Although this technology was …

Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability

K Akagi, J Li, TR Broutian, H Padilla-Nash… - Genome …, 2014 - genome.cshlp.org
Genomic instability is a hallmark of human cancers, including the 5% caused by human
papillomavirus (HPV). Here we report a striking association between HPV integration and …

Semiconductor nanocrystals as fluorescent biological labels

M Bruchez Jr, M Moronne, P Gin, S Weiss… - science, 1998 - science.org
Semiconductor nanocrystals were prepared for use as fluorescent probes in biological
staining and diagnostics. Compared with conventional fluorophores, the nanocrystals have …

[KNIHA][B] Principles of fluorescence spectroscopy

JR Lakowicz - 2006 - Springer
The success of fluorescence experiments requires attention to experimental details and an
understanding of the instrumentation. There are also many potential artifacts that can distort …

Quantum dot bioconjugates for imaging, labelling and sensing

IL Medintz, HT Uyeda, ER Goldman, H Mattoussi - Nature materials, 2005 - nature.com
One of the fastest moving and most exciting interfaces of nanotechnology is the use of
quantum dots (QDs) in biology. The unique optical properties of QDs make them appealing …

Identification of a cancer stem cell in human brain tumors

SK Singh, ID Clarke, M Terasaki, VE Bonn… - Cancer …, 2003 - aacrjournals.org
Most current research on human brain tumors is focused on the molecular and cellular
analysis of the bulk tumor mass. However, there is overwhelming evidence in some …