Systemic sclerosis-specific antibodies: novel and classical biomarkers

I Cavazzana, T Vo**ovic, P Airo', M Fredi… - Clinical Reviews in …, 2023 - Springer
Disease-specific autoantibodies are considered the most important biomarkers for systemic
sclerosis (SSc), due to their ability to stratify patients with different severity and prognosis …

Advanced autoantibody testing in systemic sclerosis

K Almaabdi, Z Ahmad, SR Johnson - Diagnostics, 2023 - mdpi.com
Systemic sclerosis is a systemic autoimmune rheumatic disease characterized by immune
abnormalities, leading to vasculopathy and fibrosis. Autoantibody testing has become an …

Autoantibodies in connective tissue disease

B Mulhearn, SL Tansley, NJ McHugh - Best Practice & Research Clinical …, 2020 - Elsevier
Autoimmune connective tissue diseases are heterogeneous rheumatic diseases with the
potential to affect multiple body systems. Autoantibodies are a characteristic feature of these …

Autoantibodies associated with systemic sclerosis in three autoimmune diseases imprinted by type I interferon gene dysregulation: a comparison across SLE, primary …

R Andraos, A Ahmad, P Eriksson… - Lupus Science & …, 2022 - lupus.bmj.com
Objective SLE, primary Sjögren's syndrome (pSS) and systemic sclerosis (SSc) are
heterogeneous autoimmune diseases with a dysregulated type I interferon (IFN) system. The …

Autoantibody profiles in systemic sclerosis; a comparison of diagnostic tests

W Alkema, H Koenen, BE Kersten, C Kaffa… - …, 2021 - Taylor & Francis
Objectives Autoimmune antibody profiling plays a prominent role in both classification and
prognosis of systemic sclerosis (SSc). In the last years novel autoantibodies have been …

Dynamic prediction of pulmonary hypertension in systemic sclerosis using landmark analysis

SI Nihtyanova, BE Schreiber, VH Ong… - Arthritis & …, 2023 - Wiley Online Library
Objective Pulmonary hypertension (PH) is a serious complication of systemic sclerosis
(SSc). In this study, we explored the prediction of short‐term risk for PH using serial …

[HTML][HTML] Diagnostic profiles for precision medicine in systemic sclerosis; step** forward from single biomarkers towards pathophysiological panels

RL Smeets, BE Kersten, I Joosten, C Kaffa… - Autoimmunity …, 2020 - Elsevier
Systemic sclerosis (SSc) is an autoimmune disease which is characterized by vasculopathy,
tissue fibrosis and activation of the innate and adaptive immune system. Clinical features of …

Overall mortality

DF Moore, VD Steen - Journal of Scleroderma and Related …, 2021 - journals.sagepub.com
Systemic sclerosis is a highly morbid, complex autoimmune disease that is variable both in
its phenotype and the attendant mortality driven by such manifestations. This review article …

Autoantibody predictors of gastrointestinal symptoms in systemic sclerosis

F Ahmed, RH Maclean, SI Nihtyanova, VH Ong… - …, 2022 - academic.oup.com
Objectives To assess the prevalence and burden of SSc-related gastrointestinal dysfunction
(SSc-GI) and to evaluate associations with demographic, clinical and serological …

High prevalence of malnutrition in systemic sclerosis: Results from a French monocentric cross-sectional study

V Rivet, S Riviere, R Goulabchand, B Suzon… - Nutrition, 2023 - Elsevier
Abstract Objectives Systemic sclerosis (SSc) can cause malnutrition due to frequent
gastrointestinal involvement. However, prevalence of malnutrition in SSc is poorly known …