Chemistries for DNA nanotechnology
M Madsen, KV Gothelf - Chemical reviews, 2019 - ACS Publications
The predictable nature of DNA interactions enables the programmable assembly of highly
advanced 2D and 3D DNA structures of nanoscale dimensions. The access to ever larger …
advanced 2D and 3D DNA structures of nanoscale dimensions. The access to ever larger …
Advancement of the emerging field of RNA nanotechnology
The field of RNA nanotechnology has advanced rapidly during the past decade. A variety of
programmable RNA nanoparticles with defined shape, size, and stoichiometry have been …
programmable RNA nanoparticles with defined shape, size, and stoichiometry have been …
The challenge of peptide nucleic acid synthesis
KP Nandhini, D Al Shaer, F Albericio… - Chemical Society …, 2023 - pubs.rsc.org
Peptide nucleic acids (PNAs) are an important class of DNA/RNA mimics that can hybridize
complementary chains of nucleic acids with high affinity and specificity. Because of this …
complementary chains of nucleic acids with high affinity and specificity. Because of this …
[HTML][HTML] Structural unfolding of G-quadruplexes: From small molecules to antisense strategies
G Fracchioni, S Vailati, M Grazioli, V Pirota - Molecules, 2024 - mdpi.com
G-quadruplexes (G4s) are non-canonical nucleic acid secondary structures that have
gathered significant interest in medicinal chemistry over the past two decades due to their …
gathered significant interest in medicinal chemistry over the past two decades due to their …
Spherical nucleic acids: Organized nucleotide aggregates as versatile nanomedicine
Spherical nucleic acids (SNAs) are composed of a nanoparticle core and a layer of densely
arranged oligonucleotide shells. After the first report of SNA by Mirkin and coworkers in …
arranged oligonucleotide shells. After the first report of SNA by Mirkin and coworkers in …
Molecular diagnostics for the detection and characterization of microbial pathogens
GW Procop - Clinical Infectious Diseases, 2007 - academic.oup.com
New and advanced methods of molecular diagnostics are changing the way we practice
clinical microbiology, which affects the practice of medicine. Signal amplification and real …
clinical microbiology, which affects the practice of medicine. Signal amplification and real …
Identification of single nucleotide polymorphisms by a peptide nucleic acid-based sandwich hybridization assay coupled with toehold-mediated strand displacement …
S Ding, X Yu, Y Zhao, C Zhao - Analytica Chimica Acta, 2023 - Elsevier
In this work, we developed a simple and accurate peptide nucleic acid (PNA)-based
sandwich hybridization assay for single nucleotide polymorphisms (SNPs) in the p53 gene …
sandwich hybridization assay for single nucleotide polymorphisms (SNPs) in the p53 gene …
Potential applications of peptide nucleic acid in biomedical domain
Abstract Peptide Nucleic Acid (PNA) are DNA/RNA synthetic analogs with 2‐([2‐aminoethyl]
amino) acetic acid backbone. They partake unique antisense and antigene properties, just …
amino) acetic acid backbone. They partake unique antisense and antigene properties, just …
Application of peptide nucleic acid towards development of nanobiosensor arrays
Peptide nucleic acid (PNA) is the modified DNA or DNA analogue with a neutral peptide
backbone instead of a negatively charged sugar phosphate. PNA exhibits chemical stability …
backbone instead of a negatively charged sugar phosphate. PNA exhibits chemical stability …
γ‐Substituted Peptide Nucleic Acids Constructed from L‐Lysine are a Versatile Scaffold for Multifunctional Display
EA Englund, DH Appella - Angewandte Chemie International …, 2007 - Wiley Online Library
Peptide nucleic acids (PNAs), which contain an achiral, uncharged aminoethylglycine (aeg)
backbone, bind natural nucleic acids through Watson–Crick base pairing with high affinity …
backbone, bind natural nucleic acids through Watson–Crick base pairing with high affinity …