Inflammation and immune mechanisms are crucially involved in the pathophysiology of the
development, acute damage cascades, and chronic course after ischemic stroke …

Neuroinflammation play an important role in Alzheimer's disease pathogenesis. Advances in
molecular imaging using positron emission tomography have provided insights into the time …

Rationale: Glial scars present a major obstacle for neuronal regeneration after stroke. Thus,
approaches to promote their degradation and inhibit their formation are beneficial for stroke …

Rationale: Mitochondrial dysfunction and oxidative stress occur in vascular dementia (VaD),
but the specific molecular mechanism regulating these events remains unclear. Peroxisome …

Neuroinflammation is a key pathologic hallmark of numerous neurologic diseases, however,
its exact role in vivo is yet to be fully understood. PET imaging enables investigation …

Following the impressive progress in the treatment of relapsing–remitting multiple sclerosis
(MS), the major challenge ahead is the development of treatments to prevent or delay the …

Neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease
(PD), are severe age-related disorders with complex and multifactorial causes. Recent …

Neuroinflammation, which involves microglial activation, is thought to play a key role in the
development and progression of neurodegenerative diseases and other brain pathologies …

Immunomodulatory therapies have fueled interest in targeting microglial cells as part of the
innate immune response after infection or injury. In this context, the colony-stimulating factor …

Neuroinflammation is an adaptive response of the central nervous system to diverse
potentially injurious stimuli, which is closely associated with neurodegeneration and …