Preservation of brain health is a worldwide priority. The traditional view is that the major
threats to the ageing brain lie within the brain itself. Consequently, therapeutic approaches …

Background Higher levels of pulse wave velocity (PWV) have been related with the
presence of small vessel disease that could damage the brain, in which white matter …

Few investigations have been performed between tobacco smoking, alcohol, and arterial
stiffness. The purpose of our study was to investigate the association between smoking use …

The associations between blood pressure and cannabis use remain inconsistent. The
purpose of our study was to examine gender stratified associations of cannabis use and …

Objective Atherosclerotic cardiovascular disease (ASCVD) is considered the leading cause
of mortality worldwide. Arterial stiffness, measured by arterial stiffness index (ASI), could be …

Arterial stiffness, measured by arterial stiffness index (ASI), could be considered a main
denominator in target organ damage among hypertensive subjects. Currently, no reported …

Abstract Background White matter hyperintensities (WMHs) represent diffuse small vessel
disease implicating the cardiac, systemic, and cerebral vasculatures. As the brain may be …

Objective Reduced white matter integrity is observed in bipolar disorder (BD), and is
associated with cardiovascular risk in adults. This topic is underexplored in youth, and in BD …

Objective Arterial stiffness–as measured by the aortic pulse wave velocity (aPWV)–has been
associated with biomarkers of cerebral small vessel disease (cSVD), in particular with white …

The process of healthy aging involves complex alterations in neural structures, with white
matter (WM) changes significantly impacting cognitive and motor functions. Conventional …