Disease-induced neuroinflammation and depression
Progression of major depression, a multifactorial disorder with a neuroinflammatory
signature, seems to be associated with the disruption of body allostasis. High rates of …
signature, seems to be associated with the disruption of body allostasis. High rates of …
[HTML][HTML] The HIV-1 transgenic rat model of neuroHIV
M Vigorito, KP Connaghan, SL Chang - Brain, behavior, and immunity, 2015 - Elsevier
Despite the ability of current combination anti-retroviral therapy (cART) to limit the
progression of HIV-1 to AIDS, HIV-positive individuals continue to experience neuroHIV in …
progression of HIV-1 to AIDS, HIV-positive individuals continue to experience neuroHIV in …
Positive modulators of the α7 nicotinic receptor against neuroinflammation and cognitive impairment in Alzheimer's disease
Evidence so far indicates that therapies targeting a single aspect of Alzheimer's disease
(AD) have no sufficient efficacy in diminishing long-term the progression of AD …
(AD) have no sufficient efficacy in diminishing long-term the progression of AD …
Methamphetamine increases the proportion of SIV-infected microglia/macrophages, alters metabolic pathways, and elevates cell death pathways: a single-cell …
Both substance use disorder and HIV infection continue to affect many individuals. Both
have untoward effects on the brain, and the two conditions often co-exist. In the brain …
have untoward effects on the brain, and the two conditions often co-exist. In the brain …
Transgenic mice expressing HIV-1 envelope protein gp120 in the brain as an animal model in neuroAIDS research
HIV-1 infection causes injury to the central nervous system (CNS) and is often associated
with neurocognitive disorders. One model for brain damage seen in AIDS patients is the …
with neurocognitive disorders. One model for brain damage seen in AIDS patients is the …
HIV neuropathogenesis in the presence of a disrupted dopamine system
EA Nickoloff-Bybel, TM Calderon, PJ Gaskill… - Journal of Neuroimmune …, 2020 - Springer
Antiretroviral therapy (ART) has transformed HIV into a chronic condition, lengthening and
improving the lives of individuals living with this virus. Despite successful suppression of HIV …
improving the lives of individuals living with this virus. Despite successful suppression of HIV …
Alarmins and central nervous system inflammation in HIV‐associated neurological disorders
ML Gougeon - Journal of internal medicine, 2017 - Wiley Online Library
In the era of highly active antiretroviral therapy (HAART), HIV‐1‐associated neurocognitive
disorders (HAND) persist in infected individuals with adequate immunological and …
disorders (HAND) persist in infected individuals with adequate immunological and …
Neuronal stress and injury caused by HIV-1, cART and drug abuse: converging contributions to HAND
AB Sanchez, M Kaul - Brain sciences, 2017 - mdpi.com
Multiple mechanisms appear to contribute to neuronal stress and injury underlying HIV-
associated neurocognitive disorders (HAND), which occur despite the successful …
associated neurocognitive disorders (HAND), which occur despite the successful …
Methamphetamine increases HIV infectivity in neural progenitor cells
M Skowronska, M McDonald, M Velichkovska… - Journal of Biological …, 2018 - jbc.org
HIV-1 infection and methamphetamine (METH) abuse frequently occur simultaneously and
may have synergistic pathological effects. Although HIV-positive/active METH users have …
may have synergistic pathological effects. Although HIV-positive/active METH users have …
[HTML][HTML] Crossroads of drug abuse and HIV infection: neurotoxicity and CNS reservoir
Drug abuse is a common comorbidity in people infected with HIV. HIV-infected individuals
who abuse drugs are a key population who frequently experience suboptimal outcomes …
who abuse drugs are a key population who frequently experience suboptimal outcomes …