Infection as an under-recognized precipitant of acute heart failure: prognostic and therapeutic implications

S Bezati, M Velliou, I Ventoulis, P Simitsis… - Heart Failure …, 2023 - Springer
As the prevalence of heart failure (HF) continues to rise, prompt diagnosis and management
of various medical conditions, which may lead to HF exacerbation and result in poor patient …

Insulin–heart axis: bridging physiology to insulin resistance

A Caturano, R Galiero, E Vetrano… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Insulin signaling is vital for regulating cellular metabolism, growth, and survival pathways,
particularly in tissues such as adipose, skeletal muscle, liver, and brain. Its role in the heart …

Signaling and function of cardiac autonomic nervous system receptors: Insights from the GPCR signalling universe

A Lymperopoulos, N Cora, J Maning, AR Brill… - The FEBS …, 2021 - Wiley Online Library
The two branches of the autonomic nervous system (ANS), adrenergic and cholinergic, exert
a multitude of effects on the human myocardium thanks to the activation of distinct G protein …

Catestatin as a biomarker of cardiovascular diseases: a clinical perspective

J Bozic, M Kumric, T Ticinovic Kurir, H Urlic… - Biomedicines, 2021 - mdpi.com
Accounting for almost one-third of the global mortality, cardiovascular diseases (CVDs)
represent a major global health issue. Emerging data suggest that most of the well …

Basic science of cardiac contractility modulation therapy: molecular and electrophysiological mechanisms

D Masarone, MM Kittleson, A D'Onofrio, L Falco… - Heart Rhythm, 2024 - Elsevier
In heart failure with reduced ejection fraction and heart failure with preserved ejection
fraction, profound cellular and molecular changes have recently been documented in the …

Clinical implications of uric acid in heart failure: a comprehensive review

M Kumrić, JA Borovac, TT Kurir, J Božić - Life, 2021 - mdpi.com
Affecting more than 26 million people worldwide and with rising prevalence, heart failure
(HF) represents a major global health problem. Hence, further research is needed in order to …

Stellate ganglia and cardiac sympathetic overactivation in heart failure

YL Li - International journal of molecular sciences, 2022 - mdpi.com
Heart failure (HF) is a major public health problem worldwide, especially coronary heart
disease (myocardial infarction)-induced HF with reduced ejection fraction (HFrEF), which …

[HTML][HTML] Advances in the Insulin–Heart Axis: Current Therapies and Future Directions

A Caturano, E Vetrano, R Galiero, C Sardu… - International Journal of …, 2024 - mdpi.com
The insulin–heart axis plays a pivotal role in the pathophysiology of cardiovascular disease
(CVD) in insulin-resistant states, including type 2 diabetes mellitus. Insulin resistance …

How COVID‐19 can cause autonomic dysfunctions and postural orthostatic syndrome? A Review of mechanisms and evidence

M Hassani, A Fathi Jouzdani… - Neurology and …, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is a viral disease spread by severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Because the recent pandemic has …

[HTML][HTML] Heart failure management guided by remote multiparameter monitoring: A meta-analysis

A Zito, A Restivo, G Ciliberti, R Laborante… - International Journal of …, 2023 - Elsevier
Background Several implant-based remote monitoring strategies are currently tested to
optimize heart failure (HF) management by anticipating clinical decompensation and …