Melatonin is a pleotropic molecule with numerous biological activities. Epidemiological and
experimental studies have documented that melatonin could inhibit different types of cancer …

Melatonin, more commonly known as the sleep hormone, is mainly secreted by the pineal
gland in dark conditions and regulates the circadian rhythm of the organism. Its intrinsic …

Preterm babies are highly susceptible to oxidative stress (OS) due to an imbalance between
the oxidant and antioxidant systems. The generation of free radicals (FR) induces oxidative …

Around 0.75 million babies worldwide suffer from moderate or severe hypoxic-ischemic
encephalopathy (HIE) each year resulting in around 400,000 babies with …

The role of melatonin has been extensively investigated in pathophysiological conditions,
including autism spectrum disorder (ASD). Reduced melatonin secretion has been reported …

Objective Melatonin has shown neuroprotective properties in pre-clinical studies of perinatal
asphyxia through antioxidant, anti-apoptotic and anti-inflammatory actions. Studies have …

Objective: The prevalence of sleep disorders during the perinatal period is high and large
health administrative database surveys have shown that the use of exogenous melatonin in …

Human pregnancy is a sequence of events finely tuned by several molecular interactions
that come with a new birth. The precise interlocking of these events affecting the …

Introduction. Preterm infants are at risk of free radical‐mediated diseases from oxidative
stress (OS) injury. Increased free radical generation has been demonstrated in preterm …

Reactive oxygen species have a crucial role in the pathogenesis of perinatal diseases.
Exposure to inflammation, infections, or high oxygen concentrations is frequent in preterm …