Vitiligo: a comprehensive overview: part I. Introduction, epidemiology, quality of life, diagnosis, differential diagnosis, associations, histopathology, etiology, and work …

A Alikhan, LM Felsten, M Daly… - Journal of the American …, 2011 - Elsevier
Vitiligo is an acquired pigmentary disorder of unknown etiology that is clinically
characterized by the development of white macules related to the selective loss of …

Vitiligo: interplay between oxidative stress and immune system

NC Laddha, M Dwivedi, MS Mansuri… - Experimental …, 2013 - Wiley Online Library
Vitiligo is a multifactorial polygenic disorder with a complex pathogenesis, linked with both
genetic and non‐genetic factors. The precise modus operandi for vitiligo pathogenesis has …

FDA approves Ruxolitinib (Opzelura) for Vitiligo Therapy: A breakthrough in the field of dermatology

A Sheikh, W Rafique, R Owais, F Malik… - Annals of medicine and …, 2022 - journals.lww.com
Abstract The Food and Drug Administration (FDA) has authorized Ruxolitinib (Opzelura), as
first at-home treatment for non-segmental vitiligo, an autoimmune condition that causes …

Gender differences in depression, co**, stigma, and quality of life in patients of vitiligo

NS Sawant, NA Vanjari… - Dermatology research and …, 2019 - Wiley Online Library
Though vitiligo is one of the psychodermatological disorders which do not cause direct
physical impairment, it is cosmetically disfiguring leading to serious psychological problems …

Increased Tumor Necrosis Factor (TNF)-α and its promoter polymorphisms correlate with disease progression and higher susceptibility towards vitiligo

NC Laddha, M Dwivedi, R Begum - PloS one, 2012 - journals.plos.org
Abstract Tumor Necrosis Factor (TNF)-α, is a paracrine inhibitor of melanocytes, which plays
a critical role in the pathogenesis of several autoimmune diseases including vitiligo, as …

Circulatory levels of antioxidants and lipid peroxidation in Indian patients with generalized and localized vitiligo

R Khan, A Satyam, S Gupta, VK Sharma… - Archives of …, 2009 - Springer
Vitiligo is an acquired skin disease, characterized by white areas on the skin due to loss of
functional melanocytes. The pathogenesis of the disease is still unclear. Published data …

Association of Neuropeptide Y (NPY), Interleukin-1B (IL1B) Genetic Variants and Correlation of IL1B Transcript Levels with Vitiligo Susceptibility

NC Laddha, M Dwivedi, MS Mansuri, M Singh… - PLoS …, 2014 - journals.plos.org
Background Vitiligo is a depigmenting disorder resulting from loss of functional melanocytes
in the skin. NPY plays an important role in induction of immune response by acting on a …

Involvement of interferon-gamma genetic variants and intercellular adhesion molecule-1 in onset and progression of generalized vitiligo

M Dwivedi, NC Laddha, K Shah, BJ Shah… - Journal of Interferon & …, 2013 - liebertpub.com
Interferon-gamma (IFN-γ) is a paracrine inhibitor of melanocytes and genetic variability due
to intron 1 polymorphisms in IFNG has been reported to be associated with increased risk for …

Interleukin‐4 genetic variants correlate with its transcript and protein levels in patients with vitiligo

M Imran, NC Laddha, M Dwivedi… - British Journal of …, 2012 - academic.oup.com
Background Vitiligo is an acquired pigmentary disorder resulting from loss of melanocytes.
Interleukin (IL)‐4 has been shown to stimulate B‐cell proliferation, to regulate …

Association of IFN‐γ : IL‐10 Cytokine Ratio with Nonsegmental Vitiligo Pathogenesis

Y Ala, MK Pasha, RN Rao, PL Komaravalli… - Autoimmune …, 2015 - Wiley Online Library
Background and Objectives. Cytokines regulate immune response and inflammation and
play a crucial role in depigmentation process of vitiligo. The present study aimed to estimate …