Digital gene expression analysis of two life cycle stages of the human-infective parasite, Trypanosoma brucei gambiense reveals differentially expressed clusters of …

NJ Veitch, PCD Johnson, U Trivedi, S Terry… - BMC genomics, 2010 - Springer
Background The evolutionarily ancient parasite, Trypanosoma brucei, is unusual in that the
majority of its genes are regulated post-transcriptionally, leading to the suggestion that …

Functionally related transcripts have common RNA motifs for specific RNA-binding proteins in trypanosomes

G Noé, JG De Gaudenzi, AC Frasch - BMC molecular biology, 2008 - Springer
Background Trypanosomes mostly control gene expression by post-transcriptional events
such as modulation of mRNA stability and translational efficiency. These mechanisms …

Identification and analysis of the RNA degrading complexes and machinery of Giardia lamblia using an in silico approach

CW Williams, HG Elmendorf - Bmc Genomics, 2011 - Springer
Background RNA degradation is critical to the survival of all cells. With increasing evidence
for pervasive transcription in cells, RNA degradation has gained recognition as a means of …

In vivo analysis of translation initiation sites in Plasmodium falciparum

BR Patakottu, PK Singh, P Malhotra… - Molecular biology …, 2012 - Springer
Regulation of gene expression in the malaria parasite Plasmodium falciparum is tightly
controlled and little is known about the many steps involved. One step ie translation initiation …

Changes in gene expression in the permissive larval host lightbrown apple moth (Epiphyas postvittana, Tortricidae) in response to EppoNPV (Baculoviridae) …

HS Gatehouse, J Poulton, NP Markwick… - Insect Molecular …, 2009 - Wiley Online Library
Host cell and virus gene expression were measured five days after per os inoculation of 3rd
instar lightbrown apple moth (LBAM) larvae with the Epiphyas postvittana …

Colorectal cancer disparities in Latin America: Mortality trends 1990–2019 and a paradox association with human development

CD Muzi, MP Banegas, RM Guimarães - Plos one, 2023 - journals.plos.org
Background Colorectal cancer mortality is growing in Latin America. It is known for a marked
income disparity between its countries, and there is a consistent association with …

Footprints of a trypanosomatid RNA world: pre-small subunit rRNA processing by spliced leader addition trans-splicing

MG Mayer, MG Santos, MFL Silva… - Memórias do Instituto …, 2012 - SciELO Brasil
The addition of a capped mini-exon [spliced leader (SL)] through trans-splicing is essential
for the maturation of RNA polymerase (pol) II-transcribed polycistronic pre-mRNAs in all …

Translation control in Trypanosoma brucei by mRNA cap-binding proteins and their interaction partners

F Falk - 2022 - archiv.ub.uni-heidelberg.de
Gene expression in Trypanosoma brucei lacks regulatory mechanisms at the level of RNA
polymerase II transcription. The initiation step of translation is therefore a critical point for …

Captura y aislamiento de proteínas que se unen al espaciador menor del locus de calmodulina de Trypanosoma cruzi

LA Jaén - 2022 - up-rid.up.ac.pa
Trypanosoma cruzi es el parásito protozoario causante de la enfermedad de Chagas, una
enfermedad endémica en Panamá. En este parásito, el proceso de regulación de la …

Networks of gene expression control in Trypanosoma brucei

K Bajak - 2019 - archiv.ub.uni-heidelberg.de
Since in trypanosomes most protein-coding genes are constitutively transcribed by RNA
polymerase II in a polycistronic manner, gene expression is mainly regulated at the post …